Small Animal Clinical Trials

The University of Florida Small Animal Hospital offers Clinical Trials for dogs, cats, and other small animals to determine efficacy and safety for future treatments, therapies, and diagnostic tools.

Please call (352) 392-2235 or email VM-ClinicalStudies@ufl.edu to be directed to a clinical trial that may suit your pet’s needs.

Current Clinical Trials in Dogs:

Internal Medicine

• Investigating Gastroduodenal Ulceration in Canine Liver Disease
• Energy Needs of ‘Giant’ Breed Dogs while Resting and Exercising on a Treadmill
• Canine Diabetes Mellitus Study
• Gut Microbiome in Canine Diabetes

Neurology

• Autogenic Vaccine Study in Dogs with Glioma (Brain Tumor)
• Use of Hemp Based Nutraceuticals as an Adjunctive Agent in Dogs with Epilepsy

Cancer

• **NEW SUMMER 2019** A Pilot Study to Determine the Safety and Efficacy of CBD Oil Use During Chemotherapy in Dogs with Lymphoma
• Evaluation of Outcome for Dogs Receiving L-asparaginase and Prednisone Dual Therapy for Palliative Treatment of Naïve High Grade Lymphoma
• Vaccine Study for Dogs with Osteosarcoma
• Vaccine Study for Dogs with Melanoma
• Melanocortin 4 receptor antagonist in the treatment of canine cachexia

Integrative Medicine and Cancer

• Investigating the effects of Acupuncture and Herbal supplements on Side Effects Associated with Chemotherapy in Dogs with Lymphoma

Dermatology

• Investigational Vaccine for Dogs with Atopic Dermatitis
• Evaluation of Chemokines as a Biomarker for Assessing Severity of Canine Atopic Dermatitis
• Effects of the New Epiotic^® on Bacterial Load and Antimicrobial Peptides Secretion in the Ears of Atopic Dogs:
• **NEW SUMMER 2019** Investigation on the Effects of Linkskin® Spray on the Cutaneous Microbiome in Canine Atopic Dermatitis

Cardiology

• Gene Therapy for Dilated Cardiomyopathy in Dobermans
• Collection of Domesticated Animal Hearts for a Tissue Bank
• Investigation into Diet-Associated Dilated Cardiomyopathy in Dogs that are Symptomatic for Heart Disease
• Investigation into Subclinical Diet-Associated Dilated Cardiomyopathy in Healthy Golden Retrievers, Miniature Schnauzers, and Doberman Pinschers

Surgery

• Prospective Randomized Cross-Over Clinical Trial Comparing Two Different Post-Operative (Spay Surgery) Devices for Incisional Protection and Client Satisfaction
• A Comparison of Soft Palate Length and Thickness in English bulldogs Following a Staphylectomy or Folded-flap Palatoplasty
• Description of a Novel Approach for Thoracic Duct Ligation and Embolization in Dogs with Idiopathic Chylothorax
• **NEW SUMMER 2019** Characterization of the Cellular and Cytokine Constituents of Bone Marrow Concentrate in Dogs with Musculoskeletal Injury or Disease

Healthy Control Dogs Needed For Multiple Studies

• Specific breeds and mixed breeds

Current Clinical Trials in Cats:

Dermatology

• Investigational Vaccine for Cats with Feline Hypersensitivity Dermatitis