The University of Florida Small Animal Hospital offers Clinical Trials for dogs, cats, and other small animals to determine efficacy and safety for future treatments, therapies, and diagnostic tools.

Please call (352) 392-2235 or email VM-ClinicalStudies@ufl.edu to be directed to a clinical trial that may suit your pet’s needs.

Current Clinical Trials in Dogs:

Internal Medicine

• Energy Needs of ‘Giant’ Breed Dogs while Resting and Exercising on a Treadmill
• Canine Diabetes Mellitus Study
• **NEW**Potential reduction of systemic and pancreatic inflammation using fenofibrate in diabetic dogs

Neurology

• Autogenic Vaccine Study in Dogs with Glioma (Brain Tumor)
• Use of Hemp Based Nutraceuticals as an Adjunctive Agent in Dogs with Epilepsy

Cancer

• Evaluation of outcomes for dogs receiving L-asparaginase and prednisone dual therapy for palliative treatment of high grade lymphoma (ON HOLD)
• A Pilot Study to Determine the Safety and Efficacy of CBD Oil Use During Chemotherapy in Dogs with Lymphoma
• Vaccine Study for Dogs with Osteosarcoma
• Vaccine Study for Dogs with Melanoma
• Melanocortin 4 receptor antagonist in the treatment of canine cachexia
• Acellular fish skin as a free xenograft for immediate wound coverage following wide surgical tumor excision in dogs
• Evaluation of real-time near-infrared fluorescence (NIRF) quantification to detect malignant lesions in the canine liver via laparotomy or laparoscopy
• Evaluation of imaging and intraoperative techniques for the identification of sentinel lymph nodes in dogs with oral tumors

Dermatology

• Investigational Vaccine for Dogs with Atopic Dermatitis
• Intradermal immunotherapy with a heat-killed actinomycetales bacterin preparation as adjunctive treatment for canine oomycoses: a multicentric, randomized, controlled, clinical trial

Cardiology

• Gene Therapy for Dilated Cardiomyopathy in Dobermans
• Collection of Domesticated Animal Hearts for a Tissue Bank

Surgery

• Prospective Randomized Cross-Over Clinical Trial Comparing Two Different Post-Operative (Spay Surgery) Devices for Incisional Protection and Client Satisfaction
• A Comparison of Soft Palate Length and Thickness in English and French bulldogs Following a Staphylectomy or Folded-flap Palatoplasty
• Description of a Novel Approach for Thoracic Duct Ligation and Embolization in Dogs with Idiopathic Chylothorax
• Characterization of the Cellular and Cytokine Constituents of Bone Marrow Concentrate in Dogs with Musculoskeletal Injury or Disease
• Evaluation of the efficacy and safety of a novel short stem total hip replacement in dogs with hip osteoarthritis secondary to hip dysplasia  (Enrollment on HOLD)

Anesthesia and Pain Management

• Erector Spinae Plane Block in Dogs Undergoing Spinal Surgery

Healthy Control Dogs Needed For Multiple Studies

• Specific breeds and mixed breeds

Current Clinical Trials in Cats:

Internal Medicine

• Exenatide Extended-Release for extending remission time in diabetic cats
• Collection of Thyroid tissue from Cats

Dermatology

• Investigational Vaccine for Cats with Feline Hypersensitivity Dermatitis

Forensic Pathology

• The Minimally Invasive Veterinary Autopsy: A Feasibility Study

Cardiology

• Fibroblast cell isolation and expansion and iPSC derivation in purebred Maine Coon and Ragdoll cats

Cancer

• Feline RNA Nanoparticle Vaccine against Oral Squamous Cell Carcinoma