Effect of supplement on skin lipid concentration in healthy dogs
Effect of supplement on skin lipid concentration in healthy dogs

The University of Florida College of Veterinary Medicine is currently recruiting healthy dogs for a clinical research trial to determine if lipid (fat) concentrations in the skin increase after supplement administration.

Inclusion Criteria:

  • Age: Over 1 year of age
  • Breed: Any breed
  • Gender: Male or Female
  • Must be able to provide past medical records as proof that your dog does not have a history of skin issues

Exclusion Criteria:

  • Dogs with any present or past dermatological conditions will be excluded from the study. Dogs with non-dermatologic systemic diseases will be evaluated on a case by case basis.

Treatment and Measurements:

In this study, you will be asked to give your dog a skin supplement or placebo once a day for 9 weeks. Your dog will be randomly assigned to either the active supplement or a placebo formulation. A loading dose will be given for one month, followed by a maintenance dose for one month, then an additional week of the maintenance dose when we will be performing evaluations. Prior to the 9-week period, measurements will be taken of the skin barrier.

All of the methods include lightly placing a probe against your dog’s skin for a few seconds. We will be taking measurements from the ear, armpit and belly. There is no discomfort or pain involved.

To perform these measurements a small area of the belly of the dog will need to be shaved two days before measurements. You will need to bring your dog in a total of eight times.

Costs: The study will cover an initial dermatological exam, the placebo or lipid supplement, and the measurements we take at designated visits. No additional costs will be covered. As an incentive, a two month dose of flea and tick preventative will be provided. This will be the flea treatment your dog is currently on.

Contacts: You can contact our Small Animal Hospital at (352) 392-2235 or email: VM-ClinicalStudies@ufl.edu to schedule an appointment with Clinical Trials. Dr. Rosanna Marsella is the Principal Investigator.

Background: In the future, this product could help dogs which suffer from atopic dermatitis. Atopic dermatitis (AD) is a common disease in both people and dogs and is characterized by chronic, progressive, inflammatory itchy skin disease. Development of safe and effective treatments to minimize these clinical signs is of great importance, especially in dogs. This study will investigate a potential treatment for this disease while having no adverse effects on the animals involved. This treatment aims to increase the concentration of lipids in the skin. Lipids are an important component of the skin barrier and it is thought that dogs with atopic dermatitis might have abnormalities in the lipid concentration in the skin. The goal of this study is to determine if the lipid supplements will show an increase in the concentration of lipids in the skin of healthy

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