Coagulation Status in Dogs with Dilated Cardiomyopathy and Atrial Fibrillation

The University of Florida College of Veterinary Medicine is currently recruiting dogs with dilated cardiomyopathy (DCM) for a study evaluating their ability to form clots.

Enrollment Criteria: Currently Enrolling

• Inclusion Criteria: Dogs that have DCM diagnosed on echocardiogram and have an electrocardiogram performed.

• Exclusion Criteria: Dogs with diseases that may predispose them to clot formation.

• Treatment: Your dog is eligible for this study if he or she has been diagnosed with DCM based on imaging diagnostic tests in the ER, ICU, or Cardiology (echocardiogram, electrocardiogram, blood pressure, etc.). Dogs with sinus rhythm and atrial fibrillation are eligible for inclusion. After enrollment, we will draw blood (less than 2 tsp) from either a catheter or vein to assess clot formation and blood cell measurements. Additionally, less than 1 tsp of urine will be collected via either a catheter, a needle into the bladder, or free catch while walking. No other interventions and no treatments will be performed on your pet as part of the study. Any other care your pet receives will be part of your pet’s standard of care treatment and will be discussed with you by your pet’s doctor.

• Cost: The study will cover the cost of the urinalysis, urine protein:creatinine ratio, von Willebrand’s testing, complete blood count, and viscoelastic testing. No other cost
• benefit is provided.

• Contact: Dr. Jake Wolf, 352-392-2235.

• PI: Dr. Jake Wolf

Background: The purpose of this study is to determine if dogs with dilated cardiomyopathy (DCM) and atrial fibrillation are prone to clot formation, which is seen in people with these diseases. Results of this study could help us identify dogs that are at risk for stroke and in need of anti-clotting medications.