March 2025 Research Publications
Genome-scale CRISPR/Cas9 screening reveals the role of PSMD4 in colibactin-mediated cell cycle arrest. Dougherty MW, Hoffmann RM, Hernandez MC, Airan Y, Gharaibeh RZ, Herzon SB, Yang Y, Jobin C. mSphere. 2025 Mar 25;10(3):e0069224. doi: 10.1128/msphere.00692-24. Epub 2025 Feb 7. PMID: 39918307 Free PMC article.
Neural gating of respiratory sensations as a potential mechanism of dyspnea perception: state-of-the-art and future directions. Jelinčić V, Chan PS, Davenport PW, von Leupoldt A. Respir Physiol Neurobiol. 2025 Mar 24:104418. doi: 10.1016/j.resp.2025.104418. Online ahead of print. PMID: 40139540
Elexacaftor/tezacaftor/ivacaftor and mental health: A workshop report from the Cystic Fibrosis Foundation’s Prioritizing Research in Mental Health working group. Bathgate CJ, Fedele DA, Tillman EM, He J, Everhart RS, Reznikov LR, Liu FF, Kirby K, Raffensperger K, Traver K, Riekert KA, Powers SW, Georgiopoulos AM. J Cyst Fibros. 2025 Mar;24(2):301-309. doi: 10.1016/j.jcf.2024.11.006. Epub 2024 Nov 26. PMID: 39592379 Review.
Breakage of cementless press-fit femoral stems following total hip arthroplasty in dogs: 14 cases (2013-2023). Carvajal JL, Karlin WM, Marcellin-Little DJ, Kowaleski MP, Verpaalen VD, Guiot LP, Chou PY, Barthelemy NP, Lotsikas PJ, Kim SE. Vet Surg. 2025 Apr;54(3):561-572. doi: 10.1111/vsu.14227. Epub 2025 Feb 19. PMID: 39967459
Neural gating of respiratory sensations as a potential mechanism of dyspnea perception: state-of-the-art and future directions. Jelinčić V, Chan PS, Davenport PW, von Leupoldt A. Respir Physiol Neurobiol. 2025 Mar 24:104418. doi: 10.1016/j.resp.2025.104418. Online ahead of print. PMID: 40139540
Outcomes associated with local treatment of nasal planum squamous cell carcinoma in dogs: 89 cases (2003-2020). Raleigh JS, Culp WTN, Giuffrida MA, Thomson C, Martin T, Mathews KG, Skinner O, Leonardi A, Bertran J, Selmic LE, Dornbusch J, Wilson J, Oblak M, Fransson B, Lux CN, Wustefeld-Janssens B, Hollenbeck D, Liptak JM, Phillips H, Selting KA, Park JE, Wallace M, Steffey MA, Balsa IM, Mayhew PD, Rebhun RB, Kent MS. J Am Vet Med Assoc. 2025 Jan 10;263(4):1-8. doi: 10.2460/javma.24.10.0642. Print 2025 Apr 1. PMID: 39793196
Generation of Population-Level Diversity in Anaplasma phagocytophilum msp2/p44 Gene Repertoires Through Recombination. Barbet AF, Allred DR, Crosby FL. Pathogens. 2025 Feb 27;14(3):233. doi: 10.3390/pathogens14030233. PMID: 40137718 Free PMC article.
Glutamate dehydrogenase has diagnostic utility for detecting liver disease in African penguins (Sphensicus demersus). Martony ME, Cray C, Delmonaco A, Nelson SE, Thompson LA, Stacy NI. Am J Vet Res. 2025 Mar 28:1-6. doi: 10.2460/ajvr.24.12.0410. Online ahead of print. PMID: 40154269
Ovarian Dynamics and Pathological Conditions in Camelids. Arroyo E, Laquiz-Silva N. Reprod Domest Anim. 2025 Mar;60(3):e70054. doi: 10.1111/rda.70054. PMID: 40145800 Review.
Comparison of remote and in-person respiratory function grading of brachycephalic dogs. Peng ZH, Ham KM, Ladlow J, Stefaniak C, Jeffery ND, Thieman Mankin KM. Vet Surg. 2025 Apr;54(3):573-580. doi: 10.1111/vsu.14171. Epub 2024 Oct 2. PMID: 39355987 Free PMC article.
Radiographic features of cardiogenic pulmonary oedema in dogs with dilated cardiomyopathy. Lee RP, Huguet EE, Adin DB, Hernandez JA, Berry CR, Vilaplana Grosso F. J Small Anim Pract. 2025 Mar 18. doi: 10.1111/jsap.13851. Online ahead of print. PMID: 40101290
Assessment of Exenatide Extended-Release for Maintenance of Diabetic Remission in Cats. Gilor C, Fleeman LM, Hulsebosch SE, Niessen SJM, Bjørnvad CR, Pires J, Hazuchova K, Mott J, O’Kell AL, Gostelow R, Rudinsky AJ, Cook AK.
J Vet Intern Med. 2025 Mar-Apr;39(2):e70069. doi: 10.1111/jvim.70069. PMID: 40105430 Free PMC article.
Accuracy of the Freestyle Libre 3 Continuous Glucose Monitoring System in Hypo- and Euglycemic Cats. Tardo AM, Crews C, Mott J, Porter LT, Adin C, Gilor C. J Vet Intern Med. 2025 Mar-Apr;39(2):e70048. doi: 10.1111/jvim.70048. PMID: 40105400 Free PMC article.
The Eye of the Largest Forest Raptor, the Harpy Eagle (Harpia harpyja): Morphologic Observations and Reference Values for Selected Ophthalmic Tests. Grego AL, de Moraes W, Moore BA, Somma AT, Ferreira TAC, Rodarte-Almeida ACV, Oriá AP, Montiani-Ferreira F. Vet Ophthalmol. 2025 Mar 16. doi: 10.1111/vop.70014. Online ahead of print. PMID: 40091145
Laparoscopic ultrasonography identifies more liver lesions in dogs compared to transabdominal ultrasonography. Solari FP, Case JB, Grosso FRV, Maxwell EA, Williams RW, Ham K, Cabrera R. Am J Vet Res. 2025 Mar 21:1-7. doi: 10.2460/ajvr.25.01.0031. Online ahead of print. PMID: 40118025
Multimodal Treatment of a Peripheral Primitive Neuroectodermal Tumor Originating From the Thoracic Cavity in a Dog. Ackerman LH, Toonder M, Bosch S, Semenova VB, Spicer TP, Alas O, Thorsen LS, Menoyo AG, Stevenson VB, Gutti JR, Saavedra PV, Nance R, Sahay B, Hery GP, Chan AM, Salute ME, Bensilmane N, Vega VF, Milner RJ. J Vet Intern Med. 2025 Mar-Apr;39(2):e70050. doi: 10.1111/jvim.70050. PMID: 40095239 Free PMC article.
A scoping review of applied tick control research in North America: funding, implementation, and advancement. Lehane Á, Mader EM, Poggi JD, McCoy KD, Gruntmeir J, Weldon CT. J Med Entomol. 2025 Mar 17;62(2):236-276. doi: 10.1093/jme/tjae155. PMID: 39739609 Review.
Effects of baclofen on swallow motor pattern. Fielder NW, Frazure M, Poliacek I, Bolser DC, Iceman KE, Pitts T. Front Neurol. 2025 Feb 25;16:1526453. doi: 10.3389/fneur.2025.1526453. eCollection 2025. PMID: 40070672 Free PMC article.
Takotsubo Cardiomyopathy-like Transient Systolic Dysfunction in Two Bald Eagles (Haliaeetus leucocephalus ). Scott S, Aherne M, Georges C, Adin DB, Wellehan JFX. J Avian Med Surg. 2025 Mar;39(1):39-45. doi: 10.1647/AVIANMS-D-23-00055. PMID: 40085122
Contrast-Enhanced Computed Tomography for Identification of Potential Malignancy in Canine Colorectal Mesenchymal Tumours. Bourgeois AD, Skinner OT, Karnia JJ, Smith AC, Kim DY, Gallastegui A, Griffin MA, O’Neill M, Wustefeld-Janssens BG, Fontes GS, Selmic LE, Traverson M, de M Souza CH, Bertran J, Thomsen B, Vinayak A, Mickelson MA. Vet Comp Oncol. 2025 Mar 8. doi: 10.1111/vco.13047. Online ahead of print. PMID: 40056897
Perspectives on lung visualization: Three-dimensional anatomical modeling of computed and micro-computed tomographic data in comparative evolutionary morphology and medicine with applications for COVID-19. Schachner ER, Lawson AB, Martinez A, Grand Pre CA, Sabottke C, Abou-Issa F, Echols S, Diaz RE Jr, Moore AJ, Grenier JP, Hedrick BP, Spieler B. Anat Rec (Hoboken). 2025 Apr;308(4):1118-1143. doi: 10.1002/ar.25300. Epub 2023 Aug 1. PMID: 37528640 Review.
Major membrane protein of Mycobacterium avium subp. paratuberculosis activates immune and autophagic pathways in bovine monocyte-derived macrophages. Kim JH, Lee D, Hall K, Jo H, Bannantine JP, Davis WC, de Souza C. Vet Immunol Immunopathol. 2025 Apr;282:110901. doi: 10.1016/j.vetimm.2025.110901. Epub 2025 Feb 21. PMID: 40015107
Update on development of monoclonal antibodies for use in clinical flow cytometry and research in dogs. de Souza C, Fidel J, Davis WC. J Vet Diagn Invest. 2025 Mar;37(2):298-304. doi: 10.1177/10406387251315530. Epub 2025 Feb 5. PMID: 39910737 Free PMC article.
Renin-Angiotensin-Aldosterone System Profiling in Horses Before and After Exercise. Holbrook T, Hernandez J, McCarrel T, Lester G, Sleeper M, Domenig O, Adin D. J Vet Intern Med. 2025 Mar-Apr;39(2):e70036. doi: 10.1111/jvim.70036. PMID: 40048547 Free PMC article.
Ultrasound-guided intercostal nerve injection in rabbit cadavers: Technique description and comparison with blind approach. Aguilar LA, Portela DA, Moura RA, Vettorato E, Otero PE, Romano M. Vet Anaesth Analg. 2025 Mar-Apr;52(2):228-235. doi: 10.1016/j.vaa.2024.12.008. Epub 2024 Dec 30. PMID: 39818484
Seroprevalence of Brucellosis in Livestock and Farmers’ Choice of Milk Marketing Channels in Rwamagana District, Rwanda. Kiiza D, Denagamage T, Kiker G, Maunsell F, Serra R, Harris-Coble LN, Benavides B, Hernandez JA. Am J Trop Med Hyg. 2024 Dec 24;112(3):497-505. doi: 10.4269/ajtmh.24-0410. Print 2025 Mar 5. PMID: 39719118 Free PMC article.
Effects of trans-mitral flow patterns and heart rate on intraventricular pressure gradients and E/E’ in the early stage of a rat model of hypertensive cardiomyopathy. Hirose M, Ma D, Shimada K, Yoshida T, Matsuura K, Kitpipatkun P, Hatanaka A, Zhao Y, Takahashi K, Tanaka R, Hamabe L. Front Vet Sci. 2025 Feb 19;12:1507817. doi: 10.3389/fvets.2025.1507817. eCollection 2025. PMID: 40046410 Free PMC article.
Targeting deubiquitinating enzymes (DUBs) and ubiquitin pathway modulators to enhance host defense against bacterial infections. Santelices J, Schultz A, Walker A, Adams N, Tirado D, Barker H, Eshraghi A, Czyż DM, Ferraro MJ. bioRxiv [Preprint]. 2025 Jan 29:2025.01.27.635188. doi: 10.1101/2025.01.27.635188. PMID: 39975367 Free PMC article. Preprint.
Evaluation of an indirect NaV 1.7 inhibitor as adjunctive analgesic in burn-related neuropathic pain in a cat. Chiavaccini L, Santoro D, Dwyer CE, Vettorato E, Nelson TS, Khanna R. Vet Anaesth Analg. 2025 Mar-Apr;52(2):257-261. doi: 10.1016/j.vaa.2025.01.004. Epub 2025 Jan 10. PMID: 39863517
Evaluation of filaggrin 2 expression in dogs with atopic dermatitis before and after oclacitinib maleate administration. Villalobos WR, Ferreira T, Borek F, Santoro D, Ferrer L, Farias M. Vet Dermatol. 2025 Mar 5. doi: 10.1111/vde.13334. Online ahead of print. PMID: 40042058
Individual and group level health factors influence social networks of dairy calves. Gingerich K, Burke KC, Maunsell FP, Miller-Cushon EK. Sci Rep. 2025 Mar 5;15(1):7720. doi: 10.1038/s41598-025-91513-y. PMID: 40044732 Free PMC article.
Periacetabular Osteotomy Improves Hip Microinstability Between Supine and Standing Radiographs in Symptomatic Hip Dysplasia. Kitamura K, Fujii M, Hamai S, Hara D, Yoshimoto K, Kawashima I, He H, Biedrzycki AH, Kawahara S, Motomura G, Nakashima Y, Banks SA. Orthop J Sports Med. 2025 Mar 4;13(3):23259671251319994. doi: 10.1177/23259671251319994. eCollection 2025 Mar. PMID: 40052180 Free PMC article.
What is your diagnosis? Mammary mass in a male dog. Dulli RJ, Badial P, Stevenson V, Whitman RE. Vet Clin Pathol. 2025 Mar 2. doi: 10.1111/vcp.13409. Online ahead of print. PMID: 40025408 No abstract available.
The economic impact of purulent vaginal discharge in dairy herds within a single lactation. Ojeda-Rojas OA, Pérez-Báez J, Casaro S, Chebel RC, Cunha F, De Vries A, Santos JEP, Lima FS, Pinedo P, Schuenemann GM, Bicalho RC, Gilbert RO, Rodriguez-Zas S, Seabury CM, Rosa G, Thatcher WW, Galvão KN. J Dairy Sci. 2025 Mar;108(3):2710-2720. doi: 10.3168/jds.2024-24897. Epub 2024 Dec 9. PMID: 39662820
Dietary fibre counters the oncogenic potential of colibactin-producing Escherichia coli in colorectal cancer. Thakur BK, Malaise Y, Choudhury SR, Neustaeter A, Turpin W, Streutker C, Copeland J, Wong EOY, Navarre WW, Guttman DS, Jobin C, Croitoru K, Martin A. Nat Microbiol. 2025 Mar 3. doi: 10.1038/s41564-025-01938-4. Online ahead of print. PMID: 40033140
The lungs of the finch: three-dimensional pulmonary anatomy of the zebra finch (Taeniopygia castanotis ). Martinez A, Diaz RE Jr, Grand Pre CA, Hedrick BP, Schachner ER. Philos Trans R Soc Lond B Biol Sci. 2025 Feb 27;380(1920):20230420. doi: 10.1098/rstb.2023.0420. Epub 2025 Feb 27. PMID: 40010384
Biology of the avian respiratory system: development, evolutionary morphology, function and clinical considerations. Maina JN, Schachner ER. Philos Trans R Soc Lond B Biol Sci. 2025 Feb 27;380(1920):20230419. doi: 10.1098/rstb.2023.0419. Epub 2025 Feb 27. PMID: 40010388 Free PMC article.
Unidirectional airflow, air sacs or the horizontal septum: what does it take to make a bird lung? Schachner ER, Moore AJ. Philos Trans R Soc Lond B Biol Sci. 2025 Feb 27;380(1920):20230418. doi: 10.1098/rstb.2023.0418. Epub 2025 Feb 27. PMID: 40010391 Free PMC article. Review.
When the lung invades: a review of avian postcranial skeletal pneumaticity. Moore AJ, Schachner ER. Philos Trans R Soc Lond B Biol Sci. 2025 Feb 27;380(1920):rstb20230427. doi: 10.1098/rstb.2023.0427. Epub 2025 Feb 27. PMID: 40010393 Review.
Retrospective comparison of minimally invasive plate osteosynthesis and open reduction and plate stabilization of antebrachial fractures in 105 dogs (2017-2022). Lederer XJ, Lewis DD, Evans RB, Johnson MD, Kim SE. Vet Surg. 2025 Feb 27. doi: 10.1111/vsu.14232. Online ahead of print. PMID: 40013457
Counterregulatory responses of healthy cats to insulin- induced-hypoglycemia. Mott J, Adin C, Crews C, Salute ME, Tardo AM, Porter L, Berg A, Gilor C. Am J Physiol Endocrinol Metab. 2025 Feb 27. doi: 10.1152/ajpendo.00269.2024. Online ahead of print. PMID: 40013934
Major membrane protein of Mycobacterium avium subp. paratuberculosis activates immune and autophagic pathways in bovine monocyte-derived macrophages. Kim JH, Lee D, Hall K, Jo H, Bannantine JP, Davis WC, de Souza C. Vet Immunol Immunopathol. 2025 Feb 21;282:110901. doi: 10.1016/j.vetimm.2025.110901. Online ahead of print. PMID: 40015107
The inability of spectral Doppler ultrasonography to identify stallions with testicular dysfunction. Pozor MA, Macpherson ML, Kelleman AA, Smith H, McNaughten JW. J Equine Vet Sci. 2025 Mar;146:105367. doi: 10.1016/j.jevs.2025.105367. Epub 2025 Feb 4. PMID: 39914506
Real-time prediction of heparin concentration in blood extracorporeal circulation by relaxation time distribution (RTD). Ueno S, Kawashima D, Matsuura K, Obara H, Tanaka R, Takei M. Bioelectrochemistry. 2025 Jun;163:108912. doi: 10.1016/j.bioelechem.2025.108912. Epub 2025 Jan 20. PMID: 39862810
Genome-wide CRISPR/Cas9 screen identifies AraC-daunorubicin-etoposide response modulators associated with outcomes in pediatric AML. Nguyen NHK, Rafiee R, Parcha PK, Tagmount A, Rubnitz J, Ribeiro R, Cao X, Pounds SB, Vulpe CD, Lamba JK. Blood Adv. 2025 Mar 11;9(5):1078-1091. doi: 10.1182/bloodadvances.2024014157. PMID: 39715471
Comparison of Survival After Treatment of Presumed Intracranial Meningioma by Radiotherapy or Surgery in 285 Dogs. Geiger R, Mankin J, Volk HA, de Decker S, van Asselt N, Randhawa K, Ehling T, Maitz CA, Naramor A, Coates JR, Stalin C, Johnstone L, Morris J, Plessas IN, Forward A, Garosi L, Scarpante E, Cherubini G, Harcourt-Brown T, Carrera-Justiz S, Gutti JR, Takada M, White J, Nagata K, Kent M, Barber R, Ito D, Nakayama T, Oshima A, Sekigucki N, Smith-Oskrochi L, Jeffery N. J Vet Intern Med. 2025 Mar-Apr;39(2):e70011. doi: 10.1111/jvim.70011. PMID: 39968764 Free PMC article.
In vitro use of a low-level laser therapy device inhibits growth of Malassezia pachydermatis. Gil N, Santoro D, Marsella R. Am J Vet Res. 2025 Feb 27:1-6. doi: 10.2460/ajvr.24.11.0355. Online ahead of print. PMID: 40014931
Advances and Challenges in Aeromonas hydrophila Vaccine Development: Immunological Insights and Future Perspectives. Miryala KR, Swain B. Vaccines (Basel). 2025 Feb 18;13(2):202. doi: 10.3390/vaccines13020202. PMID: 40006748 Free PMC article. Review.
Differences in uterine and serum metabolome associated with clinical cure failure of metritis in dairy cows. Pereira FNS, Martelo Pereira A, Galvão KN, Bisinotto RS, Figueiredo CC. Biol Reprod. 2025 Feb 23:ioaf038. doi: 10.1093/biolre/ioaf038. Online ahead of print. PMID: 39987553
2025 AAHA Referral Guidelines. Burney D, Jones G, Byers C, Campbell C, Coe JB, Gagne J, Moore BA, Pavlovsky G, Pulter C, Selke A, Van Pelt RA. J Am Anim Hosp Assoc. 2025 Mar 1;61(2):28-45. doi: 10.5326/JAAHA-MS-7489. PMID: 40009526
Current Dengue Virus Vaccine Developments and Future Directions. Anumanthan G, Sahay B, Mergia A. Viruses. 2025 Jan 31;17(2):212. doi: 10.3390/v17020212. PMID: 40006967 Free PMC article. Review.
Skin Barrier in Normal and Allergic Horses: What Do We Know? Marsella R. Vet Sci. 2025 Jan 24;12(2):91. doi: 10.3390/vetsci12020091. PMID: 40005851 Free PMC article. Review.
Comparative Patho-Genomics of Salmonella enterica Serovar Enteritidis Reveal Potential Host-Specific Virulence Factors. Moreau MR, Edison LK, Ivanov YV, Wijetunge DSS, Hewage EMKK, Linder JE, Kariyawasam S. Pathogens. 2025 Feb 1;14(2):128. doi: 10.3390/pathogens14020128. PMID: 40005504 Free PMC article.