January 2026 Research Publications

DEPARTMENT OF COMPARATIVE, DIAGNOSTIC & POPULATION MEDICINE

• Population genomics reveals an ancient origin of heartworms in canids. Power RI, Abdullah S, Walden HS, Verocai GG, Sanders TL, Luksovsky JL, Moorhead AR, Dzimianski MT, Foster JM, Michalski ML, Rojas A, Chacón SC, Deak G, Mihalca AD, Danesi P, Papadopoulos E, Taweethavonsawat P, Thi Bui D, Do Ngoc A, Sharma RSK, Ho SYW, Doyle SR, Šlapeta J. Commun Biol. 2026 Jan 20;9(1):68. doi: 10.1038/s42003-025-09250-x. Free PMC article.
  PMID: 41559308          
• Diagnostic accuracy of pulse pressure variation, stroke volume variation and plethysmography variability index for prediction of fluid responsiveness in anesthetized and mechanically ventilated dogs: a systematic review and meta-analysis. Donati PA, Tarragona L, Cordero IS, Franco JVA, Liquitay CE, Portela DA, Araos J, Staffieri F, Otero PE. Vet Anaesth Analg. 2026 Jan-Feb;53(1):101150. doi: 10.1016/j.vaa.2025.10.006. Epub 2025 Oct 27. Review.
  PMID: 41241574     
• Ultrasound-guided out-of-plane approach to the sciatic nerve in dogs: a cadaveric comparison with the caudal in-plane approach. Díaz A, Fuensalida SE, Tarragona L, Giansanti NH, Portela DA, Otero PE. Vet Anaesth Analg. 2025 Dec 16:101169. doi: 10.1016/j.vaa.2025.101169. Online ahead of print.
  PMID: 41494930     
• Latent trait-like component identified for bottlenose dolphin fecal glucocorticoid metabolite concentrations. Lauderdale LK, Granger DA, Walsh MT, Miller LJ. Gen Comp Endocrinol. 2025 Dec 28:114873. doi: 10.1016/j.ygcen.2025.114873. Online ahead of print.
  PMID: 41468925     

DEPARTMENT OF INFECTIOUS DISEASES AND IMMUNOLOGY

• Microbial-derived immunostimulatory small molecule augments anti-PD-1 therapy in lung cancer. Newsome RC, Liu H, Agbodzi B, Gharaibeh RZ, Zhou L, Jobin C. Cell Rep Med. 2026 Jan 20;7(1):102519. doi: 10.1016/j.xcrm.2025.102519. Epub 2025 Dec 19.
  PMID: 41421351     
• LSD1 Inhibition Induces MHC-I and Dendritic Cell Activation to Promote Antitumor Immunity in Head and Neck Squamous Cell Carcinoma. Chakraborty AK, Kroehling L, Raut RD, Choudhury C, Kukuruzinska MA, Gutkind JS, Varelas X, Sahay B, Monti S, Bais MV. Cancer Res. 2026 Jan 16;86(2):503-518. doi: 10.1158/0008-5472.CAN-24-3239. Free PMC article.   
  PMID: 41066547  
• Molecular Characterization and Clinicopathological Findings of Mycoplasma pogonae Infection in Captive Central Bearded Dragons (Pogona vitticeps). Plangsangmas T, Burne A, De Luca E, Sasaki E, Menk Pinto Lima JC, Konopka K, Brown MB, Nevarez JG. Animals (Basel). 2025 Dec 24;16(1):48. doi: 10.3390/ani16010048. Free PMC article.
  PMID: 41514736     

DEPARTMENT OF LARGE ANIMAL CLINICAL SCIENCES

• The interactive relationship between Fusobacterium necrophorum, Bacteroides pyogenes, and Porphyromonas levii in driving inflammatory uterine disease. Cao D, Ammad M, Subhadra B, Panda MK, Inzana TJ, Cunha F, Casaro S, Jones KL, Ramirez-Hernandez R, Bromfield JJ, Galvão KNA, Jeon SJ. Microbiome. 2026 Jan 24. doi: 10.1186/s40168-025-02320-6. Online ahead of print.
  PMID: 41580838     
• Forgotten but Back in the Spotlight: The Importance of Considering the Field of View for Obtaining White Blood Cell Estimates From Blood Films. Arnold JE, Stacy NI, Berliner A. Vet Clin Pathol. 2026 Jan 16. doi: 10.1111/vcp.70095. Online ahead of print. No abstract available.
  PMID: 41540945     
• Blood analytes relevant to nutritional status and energy metabolism in three sea turtle species across nesting season. Kaleel KL, Perrault JR, Hirsch SE, Myre BL, M Aoki D, Bishop WR, Klingshirn S, Niland H, Persaud S, Toonder M, Stacy NI. J Comp Physiol B. 2026 Jan 13. doi: 10.1007/s00360-025-01643-y. Online ahead of print. No abstract available.
  PMID: 41528446     
• Proteomic Characterization of Bottlenose Dolphin (Tursiops truncatus) Urine. Cusick KN, Bland A, Stacy NI, McFee WE, Takeshita R, Wells RS, Smith CR, Schwacke L, Janech MG. J Proteome Res. 2026 Jan 2;25(1):290-306. doi: 10.1021/acs.jproteome.5c00718. Epub 2025 Dec 13.
  PMID: 41389023     
• Endothelial glycocalyx damage is associated with small intestinal disease in horses. Hobbs KJ, Ludwig EK, Martin EM, Bayless R, Bauck AG, Freeman DE, Gonzalez LM. Am J Vet Res. 2025 Oct 14;87(1):ajvr.25.07.0251. doi: 10.2460/ajvr.25.07.0251. Print 2026 Jan 1.
  PMID: 41086830     

DEPARTMENT OF PHYSIOLOGICAL SCIENCES

• Parkinson’s disease LRRK2 mutations dysregulate iron homeostasis and promote oxidative stress and ferroptosis in human neurons and astrocytes. Mamais A, Batchelor RD Jr, Chairmandurai A, Subrahmanian N, Maio N, Vulpe CD, LaVoie MJ. bioRxiv [Preprint]. 2025 Sep 28:2025.09.26.678370. doi: 10.1101/2025.09.26.678370. Free PMC article. Preprint.
  PMID: 41542458    
• Divergent neurobehavioral effects of CFTR modulators elexacaftor and ivacaftor in mice. Ge Q, Fagan A, Lu H, Du J, Reznikov LR. Acta Psychol (Amst). 2026 Jan 13;263:106210. doi: 10.1016/j.actpsy.2026.106210. Online ahead of print. PMID: 41534408     
• Characterizing common loss-of-function genes and their potential utility in assessing population variability and chemical susceptibility. Kim C, Zhu Z, Tagmount A, Barbazuk WB, Bacher R, Stuchal LD, Martyniuk CJ, Vulpe CD.
  bioRxiv [Preprint]. 2025 Dec 19:2025.12.16.694775. doi: 10.64898/2025.12.16.694775. Free PMC article. Preprint.
  PMID: 41473284  
• Toxicophore-informed machine learning integrating Tox21 assay readouts for organ system-specific carcinogenicity prediction. Chen CY, Chou WC, Kamineni VN, Wu PY, Zhang Z, Wu X, Vulpe CD, Lin Z. Environ Pollut. 2026 Feb 1;390:127519. doi: 10.1016/j.envpol.2025.127519. Epub 2025 Dec 11.
  PMID: 41389866     

DEPARTMENT OF SMALL ANIMAL CLINICAL SCIENCES

• The Effect of Lateral Extra-articular Tenodesis Femoral Fixation Methods on Graft Failure Rates in Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-analysis. Johnson MC, Tabbaa A, Galina J, Dabas H, Erez O, Chahla J, Pearle A, Gilat R. Am J Sports Med. 2026 Jan 23:3635465251405495. doi: 10.1177/03635465251405495. Online ahead of print.
  PMID: 41572954     
• Presentation, diagnosis, and management of gossypibomas in veterinary specialty hospitals: A multi-institutional study of 21 cases. Seger CB, Regier P, Ham K, McNamara KL, Townsend KL, Risselada M, Wallace M, Buote N, Thieman KM. Vet Surg. 2026 Jan;55(1):101-109. doi: 10.1111/vsu.14307. Epub 2025 Jul 18.
  PMID: 40679240     
• Successful Use of a Single Carbon Dioxide (CO₂) Laser Procedure as Medium-To-Long-Term Treatment for Unresponsive Dermal Arteritis of the Nasal Philtrum in Dogs: A Retrospective Study. Santoro D. Vet Dermatol. 2026 Feb;37(1):132-139. doi: 10.1111/vde.70022. Epub 2025 Aug 26.
  PMID: 40856162     
• Introduction and Validation of Radiographic Guidelines for Identification of Nasoesophageal and Nasogastric Tube Position in Dogs and Cats. Vila Cabaleiro A, O’Neill DG, Cordella A, Vilaplana Grosso FR, Gioele Rizzo S, Matson HL, Porcarelli F, Bosher JC, Matkar VS, Duggan RG, Diana A, Stock E, Pearce H, Fitzgerald E. Vet Radiol Ultrasound. 2026 Jan;67(1):e70138. doi: 10.1111/vru.70138.
  PMID: 41540970     
• Feline Conjunctival Sequestra-A Case Series. da Rosa CC, Story BD, Park S, Shaw GC, Teixeira LBC, Morris J, Moore BA, Montiani-Ferreira F. Vet Ophthalmol. 2026 Jan;29(1):e70056. doi: 10.1111/vop.70056. Epub 2025 Jul 27. Free PMC article.
  PMID: 40717243 
• Navigating Inclusive Language in Veterinary Medicine: A Step Toward a More Equitable Workplace. Odunayo A, Ng Z. Vet Ophthalmol. 2026 Jan;29(1):e70025. doi: 10.1111/vop.70025. Epub 2025 May 12. Review.
  PMID: 40356033
• Diaphragmotomy enhances caudal liver displacement and hilus visualization in canine cadavers. Davey EL, Gabaldon C, Reynolds PS, Ham K, Maxwell EA, Townsend KL, Bertran J. Am J Vet Res. 2025 Dec 22:1-6. doi: 10.2460/ajvr.25.08.0297. Online ahead of print.
  PMID: 41429108     
• Characterization of incidental kratom exposure in companion animals. Maxwell EA, Mirra RA, Jeffers A. J Am Vet Med Assoc. 2025 Dec 29:1-5. doi: 10.2460/javma.25.09.0602. Online ahead of print.
  PMID: 41461137     
• Fasting improves oral bioavailability of mitragynine in healthy female Beagles. Ortiz A, Maxwell EA, Kuntz M, Gour A, Portela DA, Miscioscia E, Bertran J, Grewal M, McCurdy CR, Sharma A. Am J Vet Res. 2025 Oct 15;87(1):ajvr.25.07.0235. doi: 10.2460/ajvr.25.07.0235. Print 2026 Jan 1.
  PMID: 41092944     
• The Eye of the Largest Forest Raptor, the Harpy Eagle (Harpia harpyja): Morphologic Observations and Reference Values for Selected Ophthalmic Tests. Grego AL, de Moraes W, Moore BA, Somma AT, Ferreira TAC, Rodarte-Almeida ACV, Oriá AP, Montiani-Ferreira F. Vet Ophthalmol. 2026 Jan;29(1):e70014. doi: 10.1111/vop.70014. Epub 2025 Mar 16.
  PMID: 40091145     
• Outcome and Toxicity Profile of Stereotactic Body Radiation Therapy for Adrenal Tumours in Dogs. Thorsen L, Law K, Walz J, Coll VM, Naramor A, Maitz C, Kubicek L, Thorsen Z, Gutti JR, Takada M. Vet Comp Oncol. 2025 Dec 17. doi: 10.1111/vco.70035. Online ahead of print.
  PMID: 41410158     

Collaborations

COMPARATIVE, DIAGNOSTIC & POPULATION MEDICINE / LARGE ANIMAL CLINICAL SCIENCES

• Evaluation of the impact of acepromazine on tissue oxygenation in horses sedated with detomidine. James AL, Vettorato E, Moura RA, Azevedo TMBPR, Mallicote MF, Chiavaccini L. Res Vet Sci. 2026 Mar;200:106019. doi: 10.1016/j.rvsc.2025.106019. Epub 2025 Dec 6.
  PMID: 41456578         

INFECTIOUS DISEASES & IMMUNOLOGY / PHYSIOLOGICAL SCIENCES

• Identification of Functional Genetic Components Modulating Toxicity Response to PFOS using Genome-wide CRISPR Screens in HepG2/C3A cells. Kim C, Tagmount A, Zhu Z, Wilson F, Li D, Ostrov DA, Barbazuk WB, Bacher R, Vulpe CD. bioRxiv [Preprint]. 2025 Dec 19:2025.12.16.694451. doi: 10.64898/2025.12.16.694451. Free PMC article. Preprint.  
  PMID: 41446233         

LARGE ANIMAL CLINICAL SCIENCES / SMALL ANIMAL CLINICAL SCIENCES

• A novel 3-dimensional-printed construct provides adequate cranial abdominal visualization for lift laparoscopy in a canine cadaver model. Lubanski JM, Case JB, Perez TJ, Williams R, Biedrzycki AH, Hanlon J, Solari FP, Bertran J. Am J Vet Res. 2025 Oct 10;87(1):ajvr.25.06.0224. doi: 10.2460/ajvr.25.06.0224. Print 2026 Jan 1.
  PMID: 41072466     

SMALL ANIMAL CLINICAL SCIENCES / COMPARATIVE, DIAGNOSTIC & POPULATION MEDICINE

• Diagnostic performance of a human over-the-counter urine test to detect kratom alkaloids and metabolites in canine urine. Mirra RA, Ortiz A, Kuntz M, Gour A, Portela DA, Miscioscia E, Bertran J, McCurdy CR, Maxwell EA. Am J Vet Res. 2025 Dec 22:1-5. doi: 10.2460/ajvr.25.09.0327. Online ahead of print.
  PMID: 41429114