July 2025 Research Publications

DEPARTMENT OF COMPARATIVE, DIAGNOSTIC & POPULATION MEDICINE

• Development of a Pericapsular Knee Desensitization Technique in Dogs: An Anatomical Cadaveric Study.
  Garbin M, Moura RA, Souza YC, Cavalcanti M, Stern AW, Romano M, Vettorato E, Otero PE, Portela DA. Vet Sci. 2025 Jun 19;12(6):599. doi: 10.3390/vetsci12060599.
  PMID: 40559836 Free PMC article.
• Emergence delirium in small animals: a first step towards an objective assessment.
  Mattei LI, Chiavaccini L, Spadavecchia C, Mirra A. Front Vet Sci. 2025 Jun 18;12:1623761. doi: 10.3389/fvets.2025.1623761. eCollection 2025.
  PMID: 40607349 Free PMC article.
• Molecular characterization of Spirometra isolates across the USA.
  Sanders TL, Sobotyk C, Jimenez Castro PD, Abdu A, Baade J, Borst M, Dangoudoubiyam S, Delcambre BA, Gruntmeir JM, Lee A, Leutenegger C, Lozoya C, Murphy G, Pulaski C, Schaefer J, Vatta A, Walden HDS, Lejeune M, Verocai GG. Parasitology. 2025 Apr;152(5):477-486. doi: 10.1017/S003118202500054X.
  PMID: 40237290
• Distribution and prevalence of Baylisascaris in domestic dogs in the United States and Canada, 2017-2023.
  Jones H, Jimenez Castro PD, Burton W, Sobotyk C, Verocai GG, Nagamori Y, Warren Z, Marsh A, Pulaski C, Walden HSD, Mitchell AM, Herrin BH, Jesudoss Chelladurai JRJ, Yabsley MJ. One Health. 2025 Jun 2;20:101095. doi: 10.1016/j.onehlt.2025.101095. eCollection 2025 Jun.
  PMID: 40585485 Free PMC article.
• Pathologic and Parasitologic Findings of Free-Ranging Yacare Caiman (Caiman yacare) in the Brazilian Pantanal.
  Gorza LL, Oliveira EC, Marcelino SAC, Nóbrega YC, Pinto HA, Tavares GC, Carvalho MPN, Santos MRD, Coutinho ME, Ossiboff RJ, Pierezan F. J Wildl Dis. 2025 Jul 1;61(3):685-693. doi: 10.7589/JWD-D-24-00102.
  PMID: 40405408
• Comparison of Dexmedetomidine/Morphine and Xylazine/Morphine as Premedication in Isoflurane-Anesthetized Sheep.
  Akaraphutiporn E, Bunnag P, Limprasutr V, Rattanapinyopituk K, Durongphongtorn S, Pablo LS, Sharp P, Pacharinsak C, Wangdee C. J Am Assoc Lab Anim Sci. 2025 Jun 1:1-7. doi: 10.30802/AALAS-JAALAS-25-048. Online ahead of print.
  PMID: 40683628

DEPARTMENT OF INFECTIOUS DISEASES AND IMMUNOLOGY

• Heterologous signal peptide grafting enhances the immune efficacy of Salmonella vectors delivering hemagglutinin against H7N9 avian influenza virus. Sun W, Zhu R, Li YA, Li Z, Du Y, Wang S, Shi H. Vet Res. 2025 Jul 21;56(1):154. doi: 10.1186/s13567-025-01590-0.
  PMID: 40691858 Free PMC article.
• Exploring the complex interplay between oral Fusobacterium nucleatum infection, periodontitis, and robust microRNA induction, including multiple known oncogenic miRNAs. Jeepipalli S, C A, Duncan W, Krishna VM, Sahay B, Chan EKL, Kesavalu L. mSystems. 2025 Jul 22;10(7):e0173224. doi: 10.1128/msystems.01732-24. Epub 2025 Jun 25.
  PMID: 40558049 Free PMC article.
• Genomic insights into ceftazidime resistance in Burkholderia pseudomallei: discovery of A172T mutation and palindromic GC-rich repeat sequences facilitating penA duplication and amplification. Tuanyok A, Nakajima C, Noll T, Khan MSR, Khrongsee P, Yowell CA, Xiao Y-P, Wuthiekanun V, Chantratita N, Heine H, Subramaniam K, Suzuki Y, Limmathurotsakul D, Mergia A. Antimicrob Agents Chemother. 2025 Jul 21:e0022025. doi: 10.1128/aac.00220-25. Online ahead of print.
  PMID: 40689768
• Exploring the complex interplay between oral Fusobacterium nucleatum infection, periodontitis, and robust microRNA induction, including multiple known oncogenic miRNAs.
  Jeepipalli S, C A, Duncan W, Krishna VM, Sahay B, Chan EKL, Kesavalu L. mSystems. 2025 Jun 25:e0173224. doi: 10.1128/msystems.01732-24. Online ahead of print.
  PMID: 40558049
• HLA-B Alleles with Shared Peptide Binding Specificities Define Global Risk of Cotrimoxazole-induced SCAR.
  Li Y, Gibson A, Saeed HN, Tahboub MA, Li D, Ostrov DA, Krantz MS, Mallal SA, Alves E, Chopra A, Choo L, Dodiuk-Gad RP, Kaffenberger B, Drucker AM, Goh MS, Ergen E, Micheletti R, Rosenbach M, Martin-Pozo MD, Gangula R, Williams EA, Yu A, O’Connor A, Mahan K, Kwan JT, Metcalfe D, Rashad R, Shanbhag SS, Pedretti S, Choshi P, Chimbetete T, Selim R, James I, Trubiano JA, Lehloenya R, Peter JG, Phillips EJ. medRxiv [Preprint]. 2025 May 28:2025.05.28.25328237. doi: 10.1101/2025.05.28.25328237.
  PMID: 40492078 Free PMC article. Preprint.
• Beneficial and detrimental consequences of AHR activation in intestinal infection.
  Diaz OE, Zhou L, Barrington C, Lindqvist D, Graelmann F, Wincent E, Stockinger B. bioRxiv [Preprint]. 2025 Jun 1:2025.05.28.656570. doi: 10.1101/2025.05.28.656570.
  PMID: 40502009 Free PMC article.Preprint.
• Gross pathology and epidemiological features of mule deerpox virus infections in farmed white-tailed deer (Odocoileus virginianus) in Florida.
  Cheng AC, Viadanna PHO, Moquin TL, Roldan L, Lednicky JA, Wisely SM, Subramaniam K, Campos Krauer JM. Vet Microbiol. 2025 Jun 16;307:110608. doi: 10.1016/j.vetmic.2025.110608. Online ahead of print.
  PMID: 40561781
• Anticoagulant therapy and altered tissue factor expression protect against experimental placental and cerebral malaria.
  Andrew AK, Bracken TC, Nazario-Maldonado NM, Russ BN, Gonzalvo KT, Brainard BM, Mackman N, Moore JM. PLoS Pathog. 2025 Jul 3;21(7):e1013259. doi: 10.1371/journal.ppat.1013259. Online ahead of print. PMID: 40608830
• Neuro-immune crosstalk: focus on innate lymphoid cells.
  Bostick JW, Zhou L. Trends Immunol. 2025 Jul 11:S1471-4906(25)00162-0. doi: 10.1016/j.it.2025.06.005. Online ahead of print.
  PMID: 40651882

DEPARTMENT OF LARGE ANIMAL CLINICAL SCIENCES

• Sublethal juvenile dioxin (TCDD) exposure alters sperm motility and whole-body vitellogenin parameters in adult male zebrafish (Danio rerio). Meyer DN, Gonzalez GF, Cowart JR, Haimbaugh A, Dennis NM, Baker TR. Aquat Toxicol. 2025 Jul 16;287:107496. doi: 10.1016/j.aquatox.2025.107496. Online ahead of print.
  PMID: 40684651
• Targeted reproductive management for lactating Holstein cows: Reproductive and economic outcomes of Double-Ovsynch compared with a targeted approach based on resumption of estrus.
  Chebel RC, Mirzaei A, Peixoto PMG, Factor L, Montevecchio AB, Bisinotto RS, De Vries A, Galvão KN, Bilby TR, Jones K.
  J Dairy Sci. 2025 Jul;108(7):7144-7164. doi: 10.3168/jds.2024-25909. Epub 2025 Feb 20.
  PMID: 39986451
• Laboratory and semifield data indicate that vector Culicoides spp. in Florida are susceptible to permethrin.
  Cooper VM, Buckner EA, Campos-Krauer JM, Wisely SM, Burkett-Cadena N. J Med Entomol. 2025 Jun 26:tjaf077. doi: 10.1093/jme/tjaf077. Online ahead of print.
  PMID: 40569815
• Prevalence of and risk factors for antimicrobial-resistant fecal bacteria in beef cow-calf operations: A systematic review.
  Ali A, Denagamage T, Hernandez JA, Bittar JHJ, Lee ACY, Jeong KC, Kariyawasam S. Res Vet Sci. 2025 Jun 10;193:105761. doi: 10.1016/j.rvsc.2025.105761. Online ahead of print.
  PMID: 40544561
• Case Report: Contralateral Pregnancies Are Carried to Term in Heifers but Not in Lactating Holstein Cows.
  Gonzalez TD, Umaña-Sedo SG, Casaro S, Hernandez ME, Bisinotto RS, Monteiro PLJ, Galvão KN. Reprod Domest Anim. 2025 Jul;60(7):e70090. doi: 10.1111/rda.70090.
  PMID: 40590607
• OPTIMIZATION OF A CROSSMATCHING PROTOCOL IN LOGGERHEAD SEA TURTLES (CARETTA CARETTA) AND INVESTIGATION OF HETEROLOGOUS TRANSFUSION COMPATIBILITY WITH GREEN SEA TURTLES (CHELONIA MYDAS).
  Shusterman LAE, Stacy NI, Norton TM, Zirkelbach B, Cashin K, Barron H, DiRocco S, Zachariah TT, Donnelly KA. J Zoo Wildl Med. 2025 Jun;56(2):392-401. doi: 10.1638/2024-0032.
  PMID: 40638180

DEPARTMENT OF PHYSIOLOGICAL SCIENCES

• Mechanistic insights into microplastic-induced reproductive toxicity in aquatic organisms: A comprehensive review. Hasan AKMM, Hossain MF, Uddin M, Khan MT, Saif UM, Hamed M, Martyniuk CJ, Chivers DP. Aquat Toxicol. 2025 Sep;286:107478. doi: 10.1016/j.aquatox.2025.107478. Epub 2025 Jul 1.
  PMID: 40651185 Review.
• Occurrence and Toxicity Mechanisms of Perfluorononanoic Acid, Perfluorodecanoic Acid, and Perfluoroundecanoic Acid in Fish: A Review.
  Ivantsova E, Sultan A, Martyniuk CJ. Toxics. 2025 May 26;13(6):436. doi: 10.3390/toxics13060436.
  PMID: 40559910 Free PMC article.Review.
• Hypochlorite-Driven Oxidative Dissolution Boosts Neurodevelopmental Toxicity of Cadmium Sulfide Nanoparticles in Zebrafish.
  Ye X, Xie Y, Liang Z, Wang S, Zhou L, Wang X, Martyniuk CJ, Yan B. Environ Sci Technol. 2025 Jun 24;59(24):12008-12021. doi: 10.1021/acs.est.4c14507. Epub 2025 Jun 12.
  PMID: 40509697
• Changes in cough motor output during repetitive mechanical stimulation of the tracheobronchial tree in cats.
  Poliacek I, Martvon L, Rose MJ, Musselwhite MN, Pitts T, Bolser DC. Respir Physiol Neurobiol. 2025 Aug-Sep;336:104457. doi: 10.1016/j.resp.2025.104457. Epub 2025 Jun 6.
  PMID: 40482795
• Leveraging intrinsic non-sinusoidal patterns to infer search behavior to predict exposure to respiratory stressors.
  Bimal A, Beres SL, Ribeiro Rodrigues V, Smith BK, Davenport PW, Napoli NJ. Am J Physiol Lung Cell Mol Physiol. 2025 Jul 1;329(1):L134-L160. doi: 10.1152/ajplung.00379.2024. Epub 2025 May 27.
  PMID: 40423964
• Neural gating of respiratory sensations as a potential mechanism of dyspnea perception: State-of-the-art and future directions.
  Jelinčić V, Chan PS, Davenport PW, von Leupoldt A. Respir Physiol Neurobiol. 2025 Aug-Sep;336:104418. doi: 10.1016/j.resp.2025.104418. Epub 2025 Mar 24.
  PMID: 40139540 Review.
• Mechanistic insights into microplastic-induced reproductive toxicity in aquatic organisms: A comprehensive review.
  Hasan AKMM, Hossain MF, Uddin M, Khan MT, Saif UM, Hamed M, Martyniuk CJ, Chivers DP. Aquat Toxicol. 2025 Jul 1;286:107478. doi: 10.1016/j.aquatox.2025.107478. Online ahead of print.
  PMID: 40651185 Review.
• A comprehensive review on the neurobehavioural effects of bisphenol compounds and the underlying molecular mechanisms in zebrafish (Danio rerio).
  Hasan AKMM, Martyniuk CJ, Niyogi S, Chivers DP. Comp Biochem Physiol C Toxicol Pharmacol. 2025 Oct;296:110228. doi: 10.1016/j.cbpc.2025.110228. Epub 2025 May 18.
  PMID: 40393573 Review.
• Fatty Acids and Inflammatory Protein Biomarkers From Coronavirus Disease 2019 Patients.
  Bala N, Habib AH, Kozuch M, Denslow ND, Dhaliwal NS, Owings AH, Glover SC, Alli AA. Immun Inflamm Dis. 2025 Jul;13(7):e70218. doi: 10.1002/iid3.70218.
  PMID: 40626890 Free PMC article.
• Club cell-derived brain-derived neurotrophic factor regulates murine airway mechanics and mucin production in response to IL-13 in a sex-dependent manner.
  Fagan A, Sponchiado M, Mata L, Amin S, Aguirre JI, Prabhakaran S, Reznikov LR. Front Physiol. 2025 Jun 23;16:1578553. doi: 10.3389/fphys.2025.1578553. eCollection 2025.
  PMID: 40626045 Free PMC article.
• Editorial: Environmental stressors and aquatic animal immune system function.
  Martyniuk CJ, Li E, Rise ML. Front Immunol. 2025 Jul 1;16:1610969. doi: 10.3389/fimmu.2025.1610969. eCollection 2025.
  PMID: 40666522 Free PMC article. No abstract available.

DEPARTMENT OF SMALL ANIMAL CLINICAL SCIENCES

• Relationship between the shape of the tibial plateau and femorotibial contact mechanics after meniscectomy in the canine stifle. Pozzi A, Natsios P, Kim SE, Choate CJ, Conrad BP. Front Vet Sci. 2025 Jul 10;12:1441329. doi: 10.3389/fvets.2025.1441329. eCollection 2025.
  PMID: 40708999 Free PMC article.
• Counterregulatory responses of healthy cats to insulin-induced hypoglycemia. Mott J, Adin C, Crews C, Salute M, Tardo AM, Porter L, Berg A, Gilor C. Am J Physiol Endocrinol Metab. 2025 Aug 1;329(2):E276-E289. doi: 10.1152/ajpendo.00269.2024. Epub 2025 Feb 27.
  PMID: 40013934
• Prognostic factors for short-term survival of cats that experienced postattenuation neurologic signs after surgical attenuation of single congenital portosystemic shunts. Otero Balda I, Selmic LE, Stamenova P, Simpson M, Lipscomb VJ, Kummeling A, Devriendt N, de Rooster H, Grzywa KM, Tivers MS, Chanoit G, Maggiar A, Billet JP, Soto Muñoz R, Oramas A, Singh A, Mullins RA. Vet Surg. 2025 Jul;54(5):930-944. doi: 10.1111/vsu.14267. Epub 2025 May 11.
  PMID: 40349143 Free PMC article.
• Minimally invasive treatment and short-term outcomes of a caudal mediastinal paraesophageal abscess (CMPA) in two dogs.
  Biehl K, Williams RW, Scheuermann L, Vilaplana Grosso FR, Case JB. Vet Surg. 2025 Jun 26. doi: 10.1111/vsu.14301. Online ahead of print.
  PMID: 40569107
• Comparative Corneal Histomorphometry Between Birds of Different Species.
  Tozetti RAR, Moreira MVL, Araújo RLS, Hirano LQL, Moore BA, Galera PD. Biology (Basel). 2025 May 25;14(6):603. doi: 10.3390/biology14060603.
  PMID: 40563855 Free PMC article.
• Radiographic features of cardiogenic pulmonary oedema in dogs with dilated cardiomyopathy.
  Lee RP, Huguet EE, Adin DB, Hernandez JA, Berry CR, Vilaplana Grosso F. J Small Anim Pract. 2025 Jul;66(7):470-476. doi: 10.1111/jsap.13851. Epub 2025 Mar 18.
  PMID: 40101290
• Changes in hemodynamics of pulmonary artery using Flowire in a canine model of acute pulmonary thromboembolism.
  Yoshida T, Matsuura K, Uemura A, Tanaka R. Animal Model Exp Med. 2025 Jul 8. doi: 10.1002/ame2.70061. Online ahead of print.
  PMID: 40628678
• Safety, Efficacy and Doxorubicin Pharmacokinetics During Cannabidiol/Cannabidiolic Acid Rich Hemp Oil Use in Dogs With Lymphoma Undergoing CHOP Chemotherapy.
  Lejeune A, Bechtel S, Milner R, Fagman L, Leal Yepes FA, Wakshlag JJ. J Vet Intern Med. 2025 Jul-Aug;39(4):e70179. doi: 10.1111/jvim.70179.
  PMID: 40622742 Free PMC article.
• Operator experience and easily identifiable veins predict first-time intravenous catheterization success rates in dogs in an emergency room.
  Singleton L, Sumners L, Chunn B, Jupiter A, Garudadri P, Okafor C, Odunayo A. J Am Vet Med Assoc. 2025 Jul 10:1-6. doi: 10.2460/javma.25.03.0212. Online ahead of print.
  PMID: 40645223
• Evaluation of filaggrin 2 expression in dogs with atopic dermatitis before and after oclacitinib maleate administration.
  Villalobos WR, Ferreira T, Borek F, Santoro D, Ferrer L, Farias M. Vet Dermatol. 2025 Aug;36(4):453-461. doi: 10.1111/vde.13334. Epub 2025 Mar 5.
  PMID: 40042058 Free PMC article.
• Presentation, diagnosis, and management of gossypibomas in veterinary specialty hospitals: A multi-institutional study of 21 cases.
  Seger CB, Regier P, Ham K, McNamara KL, Townsend KL, Risselada M, Wallace M, Buote N, Thieman KM. Vet Surg. 2025 Jul 18. doi: 10.1111/vsu.14307. Online ahead of print.
  PMID: 40679240
• Laparoscopic ultrasonography identifies more liver lesions in dogs compared to transabdominal ultrasonography.
  Solari FP, Case JB, Grosso FRV, Maxwell EA, Williams RW, Ham K, Cabrera R. Am J Vet Res. 2025 Mar 21;86(6):ajvr.25.01.0031. doi: 10.2460/ajvr.25.01.0031. Print 2025 Jun 1.
  PMID: 40118025
• Sensitization of tumours to immunotherapy by boosting early type-I interferon responses enables epitope spreading.
  Qdaisat S, Wummer B, Stover BD, Zhang D, McGuiness J, Weidert F, Chardon-Robles J, Grippin A, DeVries A, Zhao C, Marconi C, Karachi A, Xie C, Jobin G, Liu R, Michel S, Ma X, Moor RSF, von Roemeling C, Nguyen DT, Elliott L, Thomas N, Barpujari A, Geffrard H, Campaneria Y, Ogando-Rivas E, Rabideau C, Soni D, Huang J, Carrera-Justiz S, Fredenburg K, Silver NL, Sawyer WG, Rahman M, Ligon JA, Flores CT, Lee JH, Mitchell DA, Castillo P, Mendez-Gomez HR, Sayour EJ. Nat Biomed Eng. 2025 Jul 18. doi: 10.1038/s41551-025-01380-1. Online ahead of print.
  PMID: 40681861
• Can implementing spectrum-of-care approaches in management of canine diabetes mellitus improve dog and owner outcomes?
  Mott J, Garrett LD, Gilor C. J Am Vet Med Assoc. 2025 Jul 18:1-4. doi: 10.2460/javma.25.04.0288. Online ahead of print.
  PMID: 40683306
• Comparison of tibial alignment following bent or straight interlocking nail fixation for dogs with diaphyseal tibial fractures.
  Ramsey HD, Hanlon J, Kieves NR, Kim SE. Vet Surg. 2025 Jul 19. doi: 10.1111/vsu.14291. Online ahead of print.
  PMID: 40682365

Collaborations

COMPARATIVE, DIAGNOSTIC & POPULATION MEDICINE / LARGE ANIMAL CLINICAL SCIENCES

• Prevalence of and risk factors for antimicrobial-resistant fecal bacteria in beef cow-calf operations: A systematic review.
  Ali A, Denagamage T, Hernandez JA, Bittar JHJ, Lee ACY, Jeong KC, Kariyawasam S. Res Vet Sci. 2025 Jun 10;193:105761. doi: 10.1016/j.rvsc.2025.105761. Online ahead of print.
  PMID: 40544561

INFECTIOUS DISEASES AND IMMUNOLOGY / LARGE ANIMAL CLINICAL SCIENCES

• Gross pathology and epidemiological features of mule deerpox virus infections in farmed white-tailed deer (Odocoileus virginianus) in Florida.
  Cheng AC, Viadanna PHO, Moquin TL, Roldan L, Lednicky JA, Wisely SM, Subramaniam K, Campos Krauer JM. Vet Microbiol. 2025 Aug;307:110608. doi: 10.1016/j.vetmic.2025.110608. Epub 2025 Jun 16.
  PMID: 40561781