September 2025 Research Publications

DEPARTMENT OF COMPARATIVE, DIAGNOSTIC & POPULATION MEDICINE

• The effects of positive end-expiratory pressure and end-inspiratory pause on dead space and alveolar ventilation in mechanically ventilated dogs. Portela DA, McKenzie SR, Moura RA, Gonzalez M, Donati PA, Sandez I, Araos J, Chiavaccini L, Maxwell EA, Otero PE. Vet Anaesth Analg. 2025 Aug 20:S1467-2987(25)00211-9. doi: 10.1016/j.vaa.2025.08.038. Online ahead of print.
  PMID: 40925835
• Air-test for assessing gas exchange and the potential benefit of alveolar recruitment manoeuvre in anaesthetized dogs. Sández I, Donati PA, Portela DA, Araos J. Vet Anaesth Analg. 2025 Jul 26:S1467-2987(25)00153-9. doi: 10.1016/j.vaa.2025.07.010. Online ahead of print.
  PMID: 40925836
• The Shapes of Yolk. Stacy NI, Garner MG, Alexander A, Conrado FO. Vet Clin Pathol. 2025 Sep 6. doi: 10.1111/vcp.70060. Online ahead of print.
  PMID: 40913372 No abstract available.
• Prolonged pharmacokinetic simulator-assisted propofol total intravenous infusion in a cat undergoing thoracic duct ligation. Vettorato E, James AL, Chiavaccini L, Portela DA. Vet Anaesth Analg. 2025 Sep-Oct;52(5):691-695. doi: 10.1016/j.vaa.2025.05.006. Epub 2025 May 31.
  PMID: 40544019
• Spinal cord injury in a 5 month old cat after single-shot lumbosacral epidural injection. Otero PE, Jaliquias A, Duchene A, Portela DA. Vet Anaesth Analg. 2025 Sep-Oct;52(5):628-632. doi: 10.1016/j.vaa.2024.11.003. Epub 2025 Feb 21.
  PMID: 39986919
• Cutaneous mast cell tumors in California sea lions (Zalophus californianus).  Miller BM, Stacy NI, Iredale M, Kovach-Zukin J, LaDouceur E, Colegrove K, McHale B, White G, Doescher B, Le-Bert CR, Ossiboff RJ. Vet Pathol. 2025 Sep 20:3009858251374690. doi: 10.1177/03009858251374690. Online ahead of print.
  PMID: 40974241

DEPARTMENT OF INFECTIOUS DISEASES AND IMMUNOLOGY

• Neuro-immune crosstalk: focus on innate lymphoid cells. Bostick JW, Zhou L. Trends Immunol. 2025 Aug;46(8):559-561. doi: 10.1016/j.it.2025.06.005. Epub 2025 Jul 11.
  PMID: 40651882 Review.
• Targeting deubiquitinating enzymes and ubiquitin pathway modulators to enhance host defense against bacterial infections. Santelices J, Schultz A, Walker A, Adams N, Tirado D, Barker H, Eshraghi A, Czyż DM, Ferraro MJ. mBio. 2025 Sep 3:e0031225. doi: 10.1128/mbio.00312-25. Online ahead of print.
  PMID: 40899844
• NOD-like receptors in fish: evolution, structure, immune signaling, and targeting for aquaculture vaccine adjuvants.  Swain B, Miryala KR. Front Immunol. 2025 Sep 2;16:1665071. doi: 10.3389/fimmu.2025.1665071. eCollection 2025.
  PMID: 40963628 Free PMC article. Review.
• A Case Cluster of Aseptic Meningitis Associated With a Newly Identified Recombinant Echovirus 6/Coxsackievirus B1 Enterovirus.  Cherabuddi K, Tagliamonte MS, Lednicky JA, Ostrov DA, Moquin TL, Thoomkuntla VK, Bourgeois B, Kollu VS, Iovine NM, Myers PD, Subramaniam K, Salemi M, Morris JG Jr. J Infect Dis. 2025 Sep 15;232(3):e486-e495. doi: 10.1093/infdis/jiaf247.
  PMID: 40359283 Free PMC article.
• Discovery of a novel STAT3 inhibitor: A potential application for pancreatic cancer treatment.  Yang X, Hung CN, Ybarra M, Villarreal M, Osmulski P, Gaczynska ME, Selvam C, Li D, Kho KL, Halff GA, Ostrov DA, Ghosh R, Kumar AP. Biomed Pharmacother. 2025 Oct;191:118487. doi: 10.1016/j.biopha.2025.118487. Epub 2025 Aug 29.
  PMID: 40885146
• Physiological Impacts on the Mosquito Vector Hosts Refine Vectorial Capacity Estimates of Mayaro Virus Transmission Risk.  Alonso-Palomares LA, Williams JF, Burgess ER 4th, Lednicky JA, Dinglasan RR. Viruses. 2025 Aug 23;17(9):1155. doi: 10.3390/v17091155.
  PMID: 41012583

DEPARTMENT OF LARGE ANIMAL CLINICAL SCIENCES

• Sublethal juvenile dioxin (TCDD) exposure alters sperm motility and whole-body vitellogenin parameters in adult male zebrafish (Danio rerio). Meyer DN, Gonzalez GF, Cowart JR, Haimbaugh A, Dennis NM, Baker TR. Aquat Toxicol. 2025 Oct;287:107496. doi: 10.1016/j.aquatox.2025.107496. Epub 2025 Jul 16.
  PMID: 40684651
• Effectiveness of a permethrin-treated barrier and pour-on applications against Culicoides spp. (Diptera: Ceratopogonidae) and mosquitoes (Diptera: Culicidae) on a deer farm. Cooper VM, Buckner EA, Wisely SM, Campos-Krauer JM, Burkett-Cadena ND. J Med Entomol. 2025 Sep 4:tjaf104. doi: 10.1093/jme/tjaf104. Online ahead of print.
  PMID: 40907976
• Cutaneous mast cell tumors in California sea lions (Zalophus californianus). Miller BM, Stacy NI, Iredale M, Kovach-Zukin J, LaDouceur E, Colegrove K, McHale B, White G, Doescher B, Le-Bert CR, Ossiboff RJ. Vet Pathol. 2025 Sep 20:3009858251374690. doi: 10.1177/03009858251374690. Online ahead of print.
  PMID: 40974241

DEPARTMENT OF PHYSIOLOGICAL SCIENCES

• Airway sympathectomy attenuates inflammation, transcriptional ratios of Muc5ac and Muc5b, and airway mechanic deficits in mice delivered intranasal IL-13. Trevizan-Baú P, Fagan AL, Amin SP, Reznikov LR. Am J Physiol Lung Cell Mol Physiol. 2025 Sep 12. doi: 10.1152/ajplung.00139.2025. Online ahead of print.
  PMID: 40938898
• Environmentally relevant levels of sulfamethoxazole (SMX) alter the skin and gastrointestinal microbiome of adult male and female zebrafish (Danio rerio). Iftikhar N, Konig I, Brammer-Robbins E, Kozuch M, Bisesi JH Jr, Hashmi I, Martyniuk CJ. Aquat Toxicol. 2025 Aug 19;288:107546. doi: 10.1016/j.aquatox.2025.107546. Online ahead of print.
  PMID: 40886646
• Asthma: Biomedical and Psychobiological Perspectives. Ritz T, Rosenkranz MA, Celedón JC, Davenport PW, Djukanovic R, Feldman JM, Forsythe P, Jajour NN, Vercelli D, von Leupoldt A, Wright RJ. Biopsychosoc Sci Med. 2025 Sep 1;87(7):428-444. doi: 10.1097/PSY.0000000000001410. Epub 2025 May 23.
  PMID: 40471941 Review.
• Environmentally relevant levels of sulfamethoxazole (SMX) alter the skin and gastrointestinal microbiome of adult male and female zebrafish (Danio rerio).  Iftikhar N, Konig I, Brammer-Robbins E, Kozuch M, Bisesi JH Jr, Hashmi I, Martyniuk CJ. Aquat Toxicol. 2025 Nov;288:107546. doi: 10.1016/j.aquatox.2025.107546. Epub 2025 Aug 19.
  PMID: 40886646
• Exposure to Bisphenol S and Bisphenol F Alters Gene Networks Related to Protein Translation and Neuroinflammation in SH-SY5Y Human Neuroblastoma Cells.  Guzman AP, Sanchez CL, Ivantsova E, Watkins J, Sutton SE, Souders CL 2nd, Martyniuk CJ. Toxics. 2025 Sep 12;13(9):772. doi: 10.3390/toxics13090772.
  PMID: 41012393
• Prenatal nicotine exposure induces epigenetic alterations in the Notch signaling genes in the proximal colon in rats.  Dali O, Heitz-Marchaland C, Kernanec PY, Carrion-Padilla J, Godin B, Tevosian S, Zubcevic J, Hayward LF, Smagulova F. BMC Genomics. 2025 Sep 26;26(1):836. doi: 10.1186/s12864-025-11960-9.
  PMID: 41013184 No abstract available.

DEPARTMENT OF SMALL ANIMAL CLINICAL SCIENCES

• No Correlation Between Chronic Cough and Radiographic Signs of Bronchial Narrowing in Dogs with Cardiomegaly and Left Atrial Dilation Secondary to Primary Mitral Valve Regurgitation.  van Opstal KY, Kittleson MD, Teske E, Auriemma E, van den Broek H, Spattini G, Vilaplana Grosso FR, Szatmári V. Animals (Basel). 2025 Aug 26;15(17):2510. doi: 10.3390/ani15172510.
  PMID: 40941305
• Treatment of antebrachial deformities secondary to premature closure of the distal radial physis using circular external skeletal fixation and distraction osteogenesis in skeletally immature dogs. de Moya KA, Gauthier CM, Radasch RM, Lewis DD, Kim S, Palmer RH, Bleedorn J. Vet Surg. 2025 Aug;54(6):1073-1083. doi: 10.1111/vsu.14214. Epub 2025 Jan 21.
  PMID: 39835630
• Computed Tomographic Appearance of Intraocular Silicone Oil in a Dog. Huguet E, Wanderer M, Colitz CMH, Cicchirillo V, Hayburn R. Vet Radiol Ultrasound. 2025 Sep;66(5):e70061. doi: 10.1111/vru.70061.
  PMID: 40811112
• Sensitization of tumours to immunotherapy by boosting early type-I interferon responses enables epitope spreading. Qdaisat S, Wummer B, Stover BD, Zhang D, McGuiness J, Weidert F, Chardon-Robles J, Grippin A, DeVries A, Zhao C, Marconi C, Karachi A, Xie C, Jobin G, Liu R, Michel S, Ma X, Moor RSF, von Roemeling C, Nguyen DT, Elliott L, Thomas N, Barpujari A, Geffrard H, Campaneria Y, Ogando-Rivas E, Rabideau C, Soni D, Huang J, Carrera-Justiz S, Fredenburg K, Silver NL, Sawyer WG, Rahman M, Ligon JA, Flores CT, Lee JH, Mitchell DA, Castillo P, Mendez-Gomez HR, Sayour EJ. Nat Biomed Eng. 2025 Sep;9(9):1437-1452. doi: 10.1038/s41551-025-01380-1. Epub 2025 Jul 18.
  PMID: 40681861
• Elevating the voice of credentialed veterinary technicians in scientific discourse.  Davis H, Fausak E, Odunayo A. J Am Vet Med Assoc. 2025 Sep 22;263(S2):S4-S5. doi: 10.2460/javma.263.s2.s4.
  PMID: 40997877 No abstract available.
• Operator experience and easily identifiable veins predict first-time intravenous catheterization success rates in dogs in an emergency room.  Singleton L, Sumners L, Chunn B, Jupiter A, Garudadri P, Okafor C, Odunayo A. J Am Vet Med Assoc. 2025 Jul 10;263(S2):S10-S15. doi: 10.2460/javma.25.03.0212. Print 2025 Oct 1.
  PMID: 40645223

Collaborations

COMPARATIVE, DIAGNOSTIC & POPULATION MEDICINE / INFECTIOUS DISEASES & IMMUNOLOGY / LARGE ANIMAL CLINICAL SCIENCES

• Fascioloides magna infection in a captive impala (Aepyceros melampus) in Florida, USA. Sizemore B, Cheng AC, Walden HDS, Subramaniam K, Wisely SM, Campos Krauer JM. Vet Parasitol Reg Stud Reports. 2025 Aug;63:101311. doi: 10.1016/j.vprsr.2025.101311. Epub 2025 Jul 16.
  PMID: 40803811

COMPARATIVE, DIAGNOSTIC & POPULATION MEDICINE / LARGE ANIMAL CLINICAL SCIENCES

• Feasibility, repeatability, and regional differences in thermal threshold and cold thermal latency testing in bearded dragons (Pogona vitticeps). Erdman EM, Johnson AN, Elzinga C, De Gennaro C, Alexander AB, Stacy NI, Chiavaccini L. Vet J. 2025 Oct;313:106410. doi: 10.1016/j.tvjl.2025.106410. Epub 2025 Aug 5.
  PMID: 40763835
• Cryptococcus gattii Infection in the Carpal Joint of a Goat.  Bosch SN, Badial P, Roe HA, Shua-Haim T, Alas O, Paradise H, Gallastegui A, De Gasperi D, Hawkins IK, Hoffmann AR, Lanier CJ, Arndt TP. Vet Clin Pathol. 2025 Sep 26. doi: 10.1111/vcp.70048. Online ahead of print.
  PMID: 40999868

COMPARATIVE, DIAGNOSTIC & POPULATION MEDICINE / SMALL ANIMAL CLINICAL SCIENCES

• Preoperative septic peritonitis, hypotension, and reason for surgery are risk factors for small intestine dehiscence in dogs: a directed acyclic graph approach. Donati PA, Tunesi M, Portela DA, Maxwell EA, Campana JP, Reina JP, Leydet M, Sahagian G, Ferreri A, Pallero JM, Piñeyro J, Alzate D, Nigro N, Otero PE. J Am Vet Med Assoc. 2025 Apr 16;263(9):1-8. doi: 10.2460/javma.24.12.0791. Print 2025 Sep 1.
  PMID: 40239696
• Preoperative Computed Tomography Features as Predictors of Malignancy and Survival in Canine Adrenal Tumours. Snell WL, Berger AC, Spoldi E, Dark MJ, Hurley ME, Suero MM, Farina LL, de Mello Souza CH, Bertran J, Maxwell EA. Vet Comp Oncol. 2025 Aug 21. doi: 10.1111/vco.70011. Online ahead of print.
  PMID: 40841179

COMPARATIVE, DIAGNOSTIC & POPULATION MEDICINE / LARGE ANIMAL CLINICAL SCIENCES / SMALL ANIMAL CLINICAL SCIENCES

• The effects of positive end-expiratory pressure and end-inspiratory pause on dead space and alveolar ventilation in mechanically ventilated dogs. Portela DA, McKenzie SR, Moura RA, Gonzalez M, Donati PA, Sandez I, Araos J, Chiavaccini L, Maxwell EA, Otero PE. Vet Anaesth Analg. 2025 Aug 20:S1467-2987(25)00211-9. doi: 10.1016/j.vaa.2025.08.038. Online ahead of print.
  PMID: 40925835