Janet Robishaw,
ASO DEAN & PROF
Department:
Department of Comparative, Diagnostic & Population Medicine
Business Phone:
(352) 273-8859
Business Email:
robishawj@ufl.edu
Publications
Academic Articles
2024
Post-transcriptional regulation and subcellular localization of G-protein γ7 subunit: implications for striatal function and behavioral responses to cocaine.
Frontiers in neuroanatomy.
18
[DOI] 10.3389/fnana.2024.1394659.
[PMID] 38764487.
2024
Rare GPR37L1 Variants Reveal Potential Association between GPR37L1 and Disorders of Anxiety and Migraine.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
44(19)
[DOI] 10.1523/JNEUROSCI.1226-23.2024.
[PMID] 38569927.
2024
Reimagining the research enterprise across University of Florida’s missions.
American journal of veterinary research.
85(10)
[DOI] 10.2460/ajvr.24.07.0189.
[PMID] 39260404.
2023
Assessing Adherence to Multi-Modal Oura Ring Wearables From COVID-19 Detection Among Healthcare Workers.
Cureus.
15(9)
[DOI] 10.7759/cureus.45362.
[PMID] 37849583.
2023
Rare GPR37L1 variants reveal potential roles in anxiety and migraine disorders.
bioRxiv : the preprint server for biology.
[DOI] 10.1101/2023.07.05.547546.
[PMID] 37461723.
2023
Temporal trends and geographic variations in mortality rates from tobacco and firearms in the United States.
Preventive medicine.
175
[DOI] 10.1016/j.ypmed.2023.107622.
[PMID] 37454875.
2022
Author Correction: Detection of COVID-19 using multimodal data from a wearable device: results from the first TemPredict Study.
Scientific reports.
12(1)
[DOI] 10.1038/s41598-022-08723-x.
[PMID] 35296773.
2022
Detection of COVID-19 using multimodal data from a wearable device: results from the first TemPredict Study.
Scientific reports.
12(1)
[DOI] 10.1038/s41598-022-07314-0.
[PMID] 35236896.
2021
Different biases in meta-analyses of case-control and cohort studies: an example from genomics and precision medicine.
Annals of epidemiology.
58:38-41
[DOI] 10.1016/j.annepidem.2021.02.013.
[PMID] 33640484.
2021
Family history in first degree relatives of patients with premature cardiovascular disease.
International journal of cardiology.
333:215-218
[DOI] 10.1016/j.ijcard.2021.03.026.
[PMID] 33737169.
2021
Genetics and prescription opioid use (GaPO): study design for consenting a cohort from an existing biobank to identify clinical and genetic factors influencing prescription opioid use and abuse.
BMC medical genomics.
14(1)
[DOI] 10.1186/s12920-021-01100-z.
[PMID] 34702274.
2021
Genomic surveillance to combat COVID-19: challenges and opportunities.
The Lancet. Microbe.
2(9):e481-e484
[DOI] 10.1016/S2666-5247(21)00121-X.
[PMID] 34337584.
2021
Selective Manipulation of G-Protein γ7 Subunit in Mice Provides New Insights into Striatal Control of Motor Behavior.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
41(44):9065-9081
[DOI] 10.1523/JNEUROSCI.1211-21.2021.
[PMID] 34544837.
2020
A simplified SARS-CoV-2 detection protocol for research laboratories.
PloS one.
15(12)
[DOI] 10.1371/journal.pone.0244271.
[PMID] 33338082.
2020
Assessment of Probable Opioid Use Disorder Using Electronic Health Record Documentation.
JAMA network open.
3(9)
[DOI] 10.1001/jamanetworkopen.2020.15909.
[PMID] 32886123.
2020
Characterization of genetic and phenotypic heterogeneity of obstructive sleep apnea using electronic health records.
BMC medical genomics.
13(1)
[DOI] 10.1186/s12920-020-00755-4.
[PMID] 32711518.
2020
Establishing and Maintaining Research Integrity at Academic Institutions: Challenges and Opportunities.
The American journal of medicine.
133(3):e87-e90
[DOI] 10.1016/j.amjmed.2019.08.036.
[PMID] 31520622.
2020
Multisite validation of a simple electronic health record algorithm for identifying diagnosed obstructive sleep apnea.
Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine.
16(2):175-183
[DOI] 10.5664/jcsm.8160.
[PMID] 31992429.
2020
Temporal Trends and Geographic Variations in Mortality Rates from Prescription Opioids: Lessons from Florida and West Virginia.
Southern medical journal.
113(3):140-145
[DOI] 10.14423/SMJ.0000000000001074.
[PMID] 32123930.
2019
Genomics and Precision Medicine to Combat Opioid Use Disorder.
The American journal of medicine.
132(4):395-396
[DOI] 10.1016/j.amjmed.2018.10.014.
[PMID] 30940352.
2019
Rare-variant pathogenicity triage and inclusion of synonymous variants improves analysis of disease associations of orphan G protein-coupled receptors.
The Journal of biological chemistry.
294(48):18109-18121
[DOI] 10.1074/jbc.RA119.009253.
[PMID] 31628190.
2018
Prescription of Statins to Women Poses New Clinical Challenges.
The American journal of medicine.
131(10):1139-1140
[DOI] 10.1016/j.amjmed.2018.03.034.
[PMID] 29679537.
2017
TM6SF2 rs58542926 impacts lipid processing in liver and small intestine.
Hepatology (Baltimore, Md.).
65(5):1526-1542
[DOI] 10.1002/hep.29021.
[PMID] 28027591.
2015
Geranylgeranylation signals to the Hippo pathway for breast cancer cell proliferation and migration.
Oncogene.
34(24):3095-106
[DOI] 10.1038/onc.2014.251.
[PMID] 25109332.
2014
Disruption of G-protein γ5 subtype causes embryonic lethality in mice.
PloS one.
9(3)
[DOI] 10.1371/journal.pone.0090970.
[PMID] 24599258.
2012
Preferential assembly of G-αβγ complexes directed by the γ subunits.
Sub-cellular biochemistry.
63:181-91
[DOI] 10.1007/978-94-007-4765-4_10.
[PMID] 23161139.
2012
Synergistic roles for G-protein γ3 and γ7 subtypes in seizure susceptibility as revealed in double knock-out mice.
The Journal of biological chemistry.
287(10):7121-33
[DOI] 10.1074/jbc.M111.308395.
[PMID] 22207761.
2010
Adenosine A2A receptor signaling and golf assembly show a specific requirement for the gamma7 subtype in the striatum.
The Journal of biological chemistry.
285(39):29787-96
[DOI] 10.1074/jbc.M110.142620.
[PMID] 20639202.
2009
Mice lacking the G protein gamma3-subunit show resistance to opioids and diet induced obesity.
American journal of physiology. Regulatory, integrative and comparative physiology.
297(5):R1494-502
[DOI] 10.1152/ajpregu.00308.2009.
[PMID] 19759336.
2008
Myocyte-specific M-CAT and MEF-1 elements regulate G-protein gamma 3 gene (gamma3) expression in cardiac myocytes.
DNA and cell biology.
27(7):367-76
[DOI] 10.1089/dna.2008.0754.
[PMID] 18613791.
2008
The orphan G protein-coupled receptor 161 is required for left-right patterning.
Developmental biology.
323(1):31-40
[DOI] 10.1016/j.ydbio.2008.08.001.
[PMID] 18755178.
2007
Expression of the G protein gammaT1 subunit during zebrafish development.
Gene expression patterns : GEP.
7(5):574-83
[PMID] 17306630.
2006
Runx-dependent regulation of G-protein gamma3 expression in T-cells.
Cellular immunology.
240(2):86-95
[PMID] 16904090.
2006
Zebrafish G protein gamma2 is required for VEGF signaling during angiogenesis.
Blood.
108(1):160-6
[PMID] 16537812.
2004
Mice with deficiency of G protein gamma3 are lean and have seizures.
Molecular and cellular biology.
24(17):7758-68
[PMID] 15314181.
2004
Ribozymes as tools for suppression of G protein gamma subunits.
Methods in molecular biology (Clifton, N.J.).
237:169-80
[PMID] 14501049.
2004
Translating G protein subunit diversity into functional specificity.
Current opinion in cell biology.
16(2):206-9
[PMID] 15196565.
2003
Functional genomic dissection of multimeric protein families in zebrafish.
Developmental dynamics : an official publication of the American Association of Anatomists.
228(3):555-67
[PMID] 14579392.
2003
Loss of G protein gamma 7 alters behavior and reduces striatal alpha(olf) level and cAMP production.
The Journal of biological chemistry.
278(8):6575-9
[PMID] 12488442.
2002
Ribozyme-mediated suppression of G protein gamma subunits.
Methods in enzymology.
344:435-51
[PMID] 11771402.
2001
Differential dependence of the D1 and D5 dopamine receptors on the G protein gamma 7 subunit for activation of adenylylcyclase.
The Journal of biological chemistry.
276(42):39386-93
[PMID] 11500503.
2001
Heterotrimeric G-protein betagamma-dimers in growth and differentiation.
Oncogene.
20(13):1653-60
[PMID] 11313913.
2000
A major locus for myoclonus-dystonia maps to chromosome 7q in eight families.
American journal of human genetics.
67(5):1314-9
[PMID] 11022010.
2000
Alpha-1 adrenergic signaling in a cardiac murine atrial myocyte (HL-1) cell line.
Molecular and cellular biochemistry.
214(1-2):111-9
[PMID] 11195782.
2000
Constitutively active mutants of the alpha(1a)- and the alpha(1b)-adrenergic receptor subtypes reveal coupling to different signaling pathways and physiological responses in rat cardiac myocytes.
The Journal of biological chemistry.
275(3):2087-97
[PMID] 10636913.
2000
Human G protein gamma(11) and gamma(14) subtypes define a new functional subclass.
Experimental cell research.
257(2):310-9
[PMID] 10837145.
1999
Ribozyme approach identifies a functional association between the G protein beta1gamma7 subunits in the beta-adrenergic receptor signaling pathway.
The Journal of biological chemistry.
274(24):17365-71
[PMID] 10358098.
1999
The alpha2A-adrenergic receptor discriminates between Gi heterotrimers of different betagamma subunit composition in Sf9 insect cell membranes.
The Journal of biological chemistry.
274(19):13525-33
[PMID] 10224121.
1998
Muscarinic K+ channel in the heart. Modal regulation by G protein beta gamma subunits.
The Journal of general physiology.
112(2):199-210
[PMID] 9689027.
1997
Differential coupling of alpha1-adrenoreceptor subtypes to phospholipase C and mitogen activated protein kinase in neonatal rat cardiac myocytes.
European journal of pharmacology.
339(1):77-86
[PMID] 9450619.
1997
G-protein-mediated signaling in cholesterol-enriched arterial smooth muscle cells. 1. Reduced membrane-associated G-protein content due to diminished isoprenylation of G-gamma subunits and p21ras.
Biochemistry.
36(31):9523-31
[PMID] 9235998.
1997
Receptor and G betagamma isoform-specific interactions with G protein-coupled receptor kinases.
Proceedings of the National Academy of Sciences of the United States of America.
94(6):2180-5
[PMID] 9122168.
1997
Ribozyme-mediated suppression of the G protein gamma7 subunit suggests a role in hormone regulation of adenylylcyclase activity.
The Journal of biological chemistry.
272(41):26040-8
[PMID] 9325341.
1996
G-protein alpha subunit Gi(alpha)2 mediates erythropoietin signal transduction in human erythroid precursors.
The Journal of clinical investigation.
98(8):1728-36
[PMID] 8878422.
1996
Gβγ-Mediated signaling in the heart: Implications of β and γ subunit heterogeneity.
Trends in cardiovascular medicine.
6(4):115-21
[DOI] 10.1016/1050-1738(96)00021-7.
[PMID] 21232284.
1995
Bovine brain GO isoforms have distinct gamma subunit compositions.
The Journal of biological chemistry.
270(9):4189-92
[PMID] 7876173.
1995
Isolation of cDNA clones encoding eight different human G protein gamma subunits, including three novel forms designated the gamma 4, gamma 10, and gamma 11 subunits.
The Journal of biological chemistry.
270(37):21765-71
[PMID] 7665596.
1995
Potentiation of Gi-mediated phospholipase C activation by retinoic acid in HL-60 cells. Possible role of G gamma 2.
The Journal of biological chemistry.
270(11):5901-8
[PMID] 7890721.
1995
Regions outside of the CAAX motif influence the specificity of prenylation of G protein gamma subunits.
The Journal of biological chemistry.
270(24):14835-41
[PMID] 7782351.
1995
Specificity of G protein alpha-gamma subunit interactions. N-terminal 15 amino acids of gamma subunit specifies interaction with alpha subunit.
The Journal of biological chemistry.
270(7):2946-51
[PMID] 7852373.
1995
Subunit expression of signal transducing G proteins in cardiac tissue: implications for phospholipase C-beta regulation.
Journal of molecular and cellular cardiology.
27(1):471-84
[PMID] 7760367.
1994
Cloning and sequencing of a rat heart cDNA encoding a G-protein beta subunit related to the human retinal beta 3 subunit.
Gene.
149(2):337-40
[PMID] 7959013.
1994
Direct interaction of the alpha and gamma subunits of the G proteins. Purification and analysis by limited proteolysis.
The Journal of biological chemistry.
269(5):3574-80
[PMID] 8106401.
1994
G protein beta gamma subunits. Simplified purification and properties of novel isoforms.
The Journal of biological chemistry.
269(6):4388-95
[PMID] 8308009.
1994
Ins 1,4,5-P3 and Ca2+ signaling in quiescent neonatal cardiac myocytes.
Biochimica et biophysica acta.
1224(3):517-26
[PMID] 7803511.
1994
Localization of a heterotrimeric G protein gamma subunit to focal adhesions and associated stress fibers.
The Journal of cell biology.
126(3):811-9
[PMID] 8045942.
1994
Preparation, characterization, and use of antibodies with specificity for G-protein gamma subunits.
Methods in enzymology.
237:498-509
[PMID] 7935023.
1994
Role of carboxylmethylation in chemoattractant receptor-stimulated G protein activation and functional responses.
Biochemical and biophysical research communications.
200(3):1604-14
[PMID] 8185616.
1994
Structure and function of G proteins mediating signal transduction pathways in the heart.
Alcoholism, clinical and experimental research.
18(1):115-20
[PMID] 8198206.
1993
A high temperature transfer procedure for detection of G protein gamma subunits by immunoblotting.
Analytical biochemistry.
208(2):283-7
[PMID] 7680843.
1992
Expression of functional G protein beta gamma dimers of defined subunit composition using a baculovirus expression system.
The Journal of biological chemistry.
267(19):13123-6
[PMID] 1618813.
1992
G protein beta gamma subunits synthesized in Sf9 cells. Functional characterization and the significance of prenylation of gamma.
The Journal of biological chemistry.
267(32):23409-17
[PMID] 1429682.
1992
Production, processing and partial purification of functional G protein beta gamma subunits in baculovirus-infected insect cells.
The Biochemical journal.
286 ( Pt 3)(Pt 3):677-80
[PMID] 1417725.
1992
Retinal rods and cones have distinct G protein beta and gamma subunits.
Proceedings of the National Academy of Sciences of the United States of America.
89(22):10882-6
[PMID] 1438293.
1992
Selective tissue distribution of G protein gamma subunits, including a new form of the gamma subunits identified by cDNA cloning.
The Journal of biological chemistry.
267(33):24023-7
[PMID] 1385432.
1991
Effect of calcium and cAMP on Go alpha expression in neonatal rat cardiac myocytes.
The American journal of physiology.
261(4 Suppl):15-20
[DOI] 10.1152/ajpheart.1991.261.4.15.
[PMID] 1656793.
1991
Role of pertussis toxin-sensitive guanosine triphosphate-binding proteins in the response of erythroblasts to erythropoietin.
Blood.
77(3):486-92
[PMID] 1899345.
1991
The effect of culture and membrane potential on Go alpha expression in neonatal rat cardiac myocytes.
Molecular and cellular biochemistry.
104(1-2):63-72
[PMID] 1922003.
1990
Expression of G proteins in rat cardiac myocytes: effect of KCl depolarization.
The American journal of physiology.
259(2 Pt 2):H432-41
[PMID] 2117401.
1990
Influence of thyroid hormone status on expression of genes encoding G protein subunits in the rat heart.
The Journal of biological chemistry.
265(6):3553-60
[PMID] 1689305.
1990
Isoprenylation of C-terminal cysteine in a G-protein gamma subunit.
The Journal of biological chemistry.
265(30):18071-4
[PMID] 2120222.
1989
Existence of two gamma subunits of the G proteins in brain.
The Journal of biological chemistry.
264(27):15758-61
[PMID] 2506169.
1989
Metabolism of pantothenic acid in hearts of diabetic rats.
Journal of molecular and cellular cardiology.
21(7):641-9
[PMID] 2795660.
1989
Role of G proteins in the regulation of the cardiovascular system.
Annual review of physiology.
51:229-44
[PMID] 2565700.
1987
A second form of the beta subunit of signal-transducing G proteins.
Proceedings of the National Academy of Sciences of the United States of America.
84(17):6122-5
[PMID] 3114742.
1986
Deduced primary structure of the alpha subunit of the GTP-binding stimulatory protein of adenylate cyclase.
Proceedings of the National Academy of Sciences of the United States of America.
83(5):1251-5
[PMID] 3081893.
1986
Molecular basis for two forms of the G protein that stimulates adenylate cyclase.
The Journal of biological chemistry.
261(21):9587-90
[PMID] 3015900.
1985
Coenzyme A metabolism.
The American journal of physiology.
248(1 Pt 1):E1-9
[PMID] 2981478.
1985
Molecular cloning of complementary DNA for the alpha subunit of the G protein that stimulates adenylate cyclase.
Science (New York, N.Y.).
229(4719):1274-7
[PMID] 3839937.
1985
The properties and regulation of pantothenate kinase from rat heart.
The Journal of biological chemistry.
260(29):15745-51
[PMID] 2999132.
1984
Differential effects of cysteine on protein and coenzyme A synthesis in rat heart.
The American journal of physiology.
247(1 Pt 1):C99-106
[PMID] 6204541.
1984
Homologies between signal transducing G proteins and ras gene products.
Science (New York, N.Y.).
226(4676):860-2
[PMID] 6436980.
1984
Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain.
The Journal of biological chemistry.
259(22):13806-13
[PMID] 6438083.
1984
Pantothenate kinase and control of CoA synthesis in heart.
The American journal of physiology.
246(4 Pt 2):H532-41
[PMID] 6326596.
1982
Control of myocardial levels of CoA and carnitine.
Journal of molecular and cellular cardiology.
14 Suppl 3:37-42
[PMID] 6754954.
1982
Rate-limiting step and control of coenzyme A synthesis in cardiac muscle.
The Journal of biological chemistry.
257(18):10967-72
[PMID] 7107640.
1981
Protection of ischemic myocardium from metabolic products.
Acta medica Scandinavica. Supplementum.
651:13-8
[PMID] 6948500.
Grants
Jul 2024
ACTIVE
The involvement of GPR37L1 on a chronic migraine-like state
Role: Principal Investigator
Funding: FL ATLANTIC UNIV
via NATL INST OF HLTH NINDS
Aug 2023
ACTIVE
New Frontiers in the prevention of Dementia
Role: Principal Investigator
Funding: FL ATLANTIC UNIV
via HARRY T MANGURIAN JR FOU
Aug 2023
– Sep 2024
Developing a precise, localized, community focused, population health framework in an FQHC to tackle chronic disease disparities through EHR data
Role: Principal Investigator
Funding: FL ATLANTIC UNIV
via NATL INST OF HLTH
Jul 2023
ACTIVE
Developing a P4 Medicine Approach to Obstructive Sleep Apnea
Role: Principal Investigator
Funding: UNIV OF PENNSYLVANIA
via NATL INST OF HLTH NHLBI
Contact Details
Phones:
- Business:
- (352) 273-8859
Emails:
- Business:
- robishawj@ufl.edu
Addresses:
- Business Street:
-
2015 SW 16TH AVE
GAINESVILLE FL 32608
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