Complete List of All Ongoing Clinical Studies

Current Clinical Trials in Dogs:

Anesthesia and Pain Management

• Effect of extradural anesthesia on postoperative complication rate in dogs undergoing total hip replacement: a prospective randomized equivalence study (Currently Enrolling)
• Evaluation of peripheral and serum biomarkers of neuropathic pruritus in dogs (Currently Enrolling)
• Controlled non-inferiority trial evaluating the use of liposomal bupivacaine on postoperative analgesia in canine hindlimb amputations (Currently Enrolling)

Cardiology

• Collection of Domesticated Animal Hearts for a Tissue Bank (Currently Enrolling)
• Gene Therapy for Dilated Cardiomyopathy in Dobermans (Currently Enrolling)
• Tolerability and Clinical Efficacy of Acetazolamide for Treatment of Hypochloremia in Canine Congestive Heart Failure (Currently Enrolling)

Dermatology

• A Field Efficacy and Safety Pilot Study of OKV-1001 for the Treatment of Chronic, Non-Seasonal Moderate-to-Severe Atopic Dermatitis (Enrollment on HOLD)
• Intradermal Immunotherapy with a Heat-Killed Actinomycetales Bacterin Preparation as Adjunctive Treatment for Canine Cutaneous Oomycoses (pythiosis): A Multicentric, Randomized, Controlled, Clinical Trial (Currently Enrolling)
• Evaluation of peripheral and serum biomarkers of neuropathic pruritus in dogs (Currently Enrolling)
• Evaluation of Staphylococcus Felis Protein Extract as a Probiotic Treatment for Canine Pyoderma (Enrollment on Hold)
• Investigation of Bacteriophage Therapy for Treatment of Pseudomonas Otitis in Dogs (Currently Enrolling)
• Investigation of New Treatment for Allergic Skin Disease in Dogs (Enrollment on HOLD)
• Investigation of Prevention Treatments for Recurrent Bacterial Otitis in Dogs (Currently Enrolling)
• Investigation of Prevention Treatments for Recurrent Otitis Externa in Allergic Dogs (Currently Enrolling)
• Investigational Vaccine for Dogs with Atopic Dermatitis (LIMITED Enrollment, must be a patient of UFVH Dermatology)
• Identifying genetic variants and microbiome (oral and skin) characteristics associated with canine atopic dermatitis and feline atopic skin syndrome (Enrollment OPEN

Integrative & Mobility Medicine

• Evaluation of the Effect of Mitragynine on Naturally Occurring Osteoarthritic Pain in a Canine Model, a Prospective, Randomized, Crossover, Double-Blinded, Placebo-Controlled Clinical Trial (Currently Enrolling)
• Surface Electromyography of the Vastus Lateralis and Gluteus Medius Muscles in Post-Operative T3-L3 Hemilaminectomy Dogs (Currently Enrolling)

Internal Medicine

• Energy Needs of ‘Giant’ Breed Dogs while Resting and Exercising on a Treadmill (Currently Enrolling)
• Evaluation of urinary biomarkers for acute kidney injury in proteinuric canine patients treated with the angiotensin II receptor blocker telmisartan (Currently Enrolling)
• Novel Biomarker and Therapeutic Target for Chronic Kidney Disease in Dogs (Currently Enrolling)

Oncology

• Vaccine Study for Dogs with Appendicular Osteosarcoma (Currently Enrolling)
• Vaccine Study for Dogs with Hemangiosarcoma (Currently Enrolling)
• Vaccine Study for Dogs with Melanoma (Currently Enrolling)
• Phase II Open-label Non-randomized Multicenter Clinical Trial of Trametinib for Dogs with Histiocytic Sarcoma (Enrollment on Hold)
• Evaluating accuracy for identification of sentinel lymph nodes in dogs with cutaneous mast cell tumors; a comparison between preoperative CT lymphography, intraoperative indocyanine green NIRF, and the standard cytology of the locoregional lymph node (Currently Enrolling)
• Phase II Open-label Non-randomized Multicenter Clinical Trial of Trametinib for Dogs With Histiocytic Sarcoma (Enrollment on HOLD)
• Controlled non-inferiority trial evaluating the use of liposomal bupivacaine on postoperative analgesia in canine hindlimb amputations (Currently Enrolling)

Surgery

• Description of Laparoscopic Ultrasound of the Liver in Healthy Dogs (Currently Enrolling)
• Investigation of Ioban Use During Canine Celiotomy to Determine Potential Benefits of Thermoregulation, Patient Dryness, and Reduction of Surgical Site Complications (Currently Enrolling)

Current Clinical Trials in Cats:

Cardiology

• Fibroblast cell isolation and expansion and iPSC derivation in purebred Maine Coon and Ragdoll cats (Currently Enrolling)

Clinical Pathology

• Toxoplasmosis in Humans; A Feline Study (Enrollment on Hold)

Dermatology

• The Effect of Probiotic vs Placebo on the Clinical Response and Cytokine Profile in Felines with Allergic Dermatitis: A Randomized, Double-Blinded Controlled Study (Currently Enrolling)
• Investigational Vaccine for Cats with Feline Hypersensitivity Dermatitis (Compassionate Enrollment ONLY)

Emergency

• CAUTIOUS (Cat Urinary Tract Infection and Obstruction Study) (Currently Enrolling)

Forensic Pathology

• The Minimally Invasive Veterinary Autopsy: A Feasibility Study (Currently Enrolling)

Internal Medicine

• Correlation of Ammonia Excretion with Renal Function in Cats with Chronic Kidney Disease (Currently Enrolling)
• Monitoring of Type 2 diabetes mellitus in cats with Felaqua: Comparison to Continuous Glucose Monitoring (CGM) (Currently Enrolling)
• Ammonia Excretion, A Novel Biomarker and Therapeutic Target for Chronic Kidney Disease in Cats. (Currently Enrolling)
• Efficacy of Potassium Citrate as a Treatment for Metabolic Acidosis in Cats with Chronic Kidney Disease (Currently Enrolling)

Oncology

• Feline RNA Nanoparticle Vaccine against Oral Squamous Cell Carcinoma (Currently Enrolling)
• Determine how LSD1 Inhibitors Alone Attenuate Feline Oral Carcinomas (Currently Enrolling)

Primary Care and Dentistry

• Analysis and Culture Results of Spontaneously Voided Urine Samples in Cats (Currently Enrolling)

Clinical Studies for Large Animals

Horses

• Collection of Domesticated Animal Hearts for a Tissue Bank (Currently Enrolling
• PET MRI of the Sport Horse Fetlock (Currently Enrolling)